Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

Rachel James; Olympia Dimopoulou; Richard M. Martin; Claire M. Perks; Claire Kelly; Louise Mathias; Stefan Brugger; Julian P. T. Higgins; Sarah J. Lewis

doi:10.3390/metabo11110726

Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

Rachel James, Olympia Dimopoulou, Richard M. Martin, Claire M. Perks, Claire Kelly, Louise Mathias, Stefan Brugger, Julian P. T. Higgins, Sarah J. Lewis

Research output: Contribution to journal › Article (Academic Journal) › peer-review

1 Citation (Scopus)

93 Downloads (Pure)

Original language	English
Article number	726
Journal	Metabolites
Volume	11
Issue number	11
DOIs	https://doi.org/10.3390/metabo11110726
Publication status	Published - 23 Oct 2021

Bibliographical note

Funding Information:
Funding: This review was funded by the World Cancer Research Fund International (grant number: WCRF 2015/1421). R.M.M., C.P. and S.J.L. were supported by a Cancer Research UK (C18281/A29019) programme grant (the Integrative Cancer Epidemiology Programme). J.P.T.H., R.M.M. and S.J.L. were supported by the NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol. J.P.T.H. was supported by the NIHR Applied Research Collaboration West at University Hospitals Bristol and Weston NHS Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the WCRF, CRUK, NIHR or the Department of Health and Social Care.

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Research Groups and Themes

ICEP

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3390/metabo11110726

Full-text PDF (final published version)
This is the final published version of the article (version of record). It first appeared online via MDPI at https://doi.org/10.3390/metabo11110726 . Please refer to any applicable terms of use of the publisher.
Final published version, 1.46 MBLicence: CC BY

Handle.net

Persistent link

Cite this

@article{05a3c1f79b594c048a09f9394fe03dcc,

title = "Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway",

author = "Rachel James and Olympia Dimopoulou and Martin, {Richard M.} and Perks, {Claire M.} and Claire Kelly and Louise Mathias and Stefan Brugger and Higgins, {Julian P. T.} and Lewis, {Sarah J.}",

note = "Funding Information: Funding: This review was funded by the World Cancer Research Fund International (grant number: WCRF 2015/1421). R.M.M., C.P. and S.J.L. were supported by a Cancer Research UK (C18281/A29019) programme grant (the Integrative Cancer Epidemiology Programme). J.P.T.H., R.M.M. and S.J.L. were supported by the NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol. J.P.T.H. was supported by the NIHR Applied Research Collaboration West at University Hospitals Bristol and Weston NHS Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the WCRF, CRUK, NIHR or the Department of Health and Social Care. Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = oct,

day = "23",

doi = "10.3390/metabo11110726",

language = "English",

volume = "11",

journal = "Metabolites",

issn = "2218-1989",

publisher = "MDPI AG",

number = "11",

}

TY - JOUR

T1 - Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

AU - James, Rachel

AU - Dimopoulou, Olympia

AU - Martin, Richard M.

AU - Perks, Claire M.

AU - Kelly, Claire

AU - Mathias, Louise

AU - Brugger, Stefan

AU - Higgins, Julian P. T.

AU - Lewis, Sarah J.

N1 - Funding Information: Funding: This review was funded by the World Cancer Research Fund International (grant number: WCRF 2015/1421). R.M.M., C.P. and S.J.L. were supported by a Cancer Research UK (C18281/A29019) programme grant (the Integrative Cancer Epidemiology Programme). J.P.T.H., R.M.M. and S.J.L. were supported by the NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol. J.P.T.H. was supported by the NIHR Applied Research Collaboration West at University Hospitals Bristol and Weston NHS Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the WCRF, CRUK, NIHR or the Department of Health and Social Care. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/10/23

Y1 - 2021/10/23

UR - https://doi.org/10.3390/metabo11110726

U2 - 10.3390/metabo11110726

DO - 10.3390/metabo11110726

M3 - Article (Academic Journal)

C2 - 34822385

SN - 2218-1989

VL - 11

JO - Metabolites

JF - Metabolites

IS - 11

M1 - 726

ER -

Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

Bibliographical note

Research Groups and Themes

UN SDGs

Access to Document

Handle.net

Other files and links

8074 (C18281/A29019) ICEP2 - Programme Award: Towards improved casual evidence and enhanced prediction of cancer risk and survival

Cite this

Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

Bibliographical note

Research Groups and Themes

UN SDGs

Access to Document

Handle.net

Other files and links

Projects

8074 (C18281/A29019) ICEP2 - Programme Award: Towards improved casual evidence and enhanced prediction of cancer risk and survival

Cite this