Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

TY - JOUR

T1 - Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

AU - James, Rachel

AU - Dimopoulou, Olympia

AU - Martin, Richard M.

AU - Perks, Claire M.

AU - Kelly, Claire

AU - Mathias, Louise

AU - Brugger, Stefan

AU - Higgins, Julian P. T.

AU - Lewis, Sarah J.

N1 - Funding Information: Funding: This review was funded by the World Cancer Research Fund International (grant number: WCRF 2015/1421). R.M.M., C.P. and S.J.L. were supported by a Cancer Research UK (C18281/A29019) programme grant (the Integrative Cancer Epidemiology Programme). J.P.T.H., R.M.M. and S.J.L. were supported by the NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol. J.P.T.H. was supported by the NIHR Applied Research Collaboration West at University Hospitals Bristol and Weston NHS Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the WCRF, CRUK, NIHR or the Department of Health and Social Care. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/10/23

Y1 - 2021/10/23

UR - https://doi.org/10.3390/metabo11110726

U2 - 10.3390/metabo11110726

DO - 10.3390/metabo11110726

M3 - Article (Academic Journal)

C2 - 34822385

SN - 2218-1989

VL - 11

JO - Metabolites

JF - Metabolites

IS - 11

M1 - 726

ER -