Cryopreservation of cells in absence of vitrification inducing agents

Robert C Deller (Inventor), Matthew I. Gibson (Inventor)

Research output: Patent

Abstract

The present invention relates to a method for cryopreserving biological material. In particular, the method comprises storing the biological material at a cryopreserving temperature in a composition comprising polyvinyl alcohol (PVA). wherein the composition is substantially free of vitrification-inducing agents such as DMSO and glycerol. The invention also provides methods of inhibiting ice recrystallisation and of reducing cell damage during the warming or thawing of a cryopreserved composition comprising biological material. The invention also relates to processes for producing a biological material, and related kits.
Original languageEnglish
Patent numberUS20150017628 A1
Priority date8/02/12
Publication statusPublished - 2015

Keywords

  • Cryopreservation
  • Biotechnology
  • Blood
  • Ice
  • Vitrification
  • PVA

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