Abstract
The present invention relates to a method for cryopreserving biological material. In particular, the method comprises storing the biological material at a cryopreserving temperature in a composition comprising polyvinyl alcohol (PVA). wherein the composition is substantially free of vitrification-inducing agents such as DMSO and glycerol. The invention also provides methods of inhibiting ice recrystallisation and of reducing cell damage during the warming or thawing of a cryopreserved composition comprising biological material. The invention also relates to processes for producing a biological material, and related kits.
| Original language | English |
|---|---|
| Patent number | US20150017628 A1 |
| Priority date | 8/02/12 |
| Publication status | Published - 2015 |
Keywords
- Cryopreservation
- Biotechnology
- Blood
- Ice
- Vitrification
- PVA