Cystic fibrosis: CFTR correctors to the rescue

DN Sheppard

doi:10.1016/j.chembiol.2011.02.003

Cystic fibrosis: CFTR correctors to the rescue

DN Sheppard

Research output: Contribution to journal › Article (Academic Journal) › peer-review

12 Citations (Scopus)

Abstract

Cystic fibrosis transmembrane conductance regulator (CFTR) correctors are small molecules that target the most common cause of cystic fibrosis: misfolded F508del-CFTR. Using differential scanning fluorimetry, Sampson et al. (2010) identify a CFTR corrector that interacts directly with the CFTR domain affected by the F508del mutation.

Translated title of the contribution	Cystic fibrosis: CFTR correctors to the rescue
Original language	English
Pages (from-to)	145 - 147
Number of pages	3
Journal	Chemistry & Biology
Volume	18
DOIs	https://doi.org/10.1016/j.chembiol.2011.02.003
Publication status	Published - Feb 2011

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Publisher: Elsevier Ltd
Other: Commentary

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10.1016/j.chembiol.2011.02.003

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@article{532b1786740046b899b3038230b373b1,

title = "Cystic fibrosis: CFTR correctors to the rescue",

abstract = "Cystic fibrosis transmembrane conductance regulator (CFTR) correctors are small molecules that target the most common cause of cystic fibrosis: misfolded F508del-CFTR. Using differential scanning fluorimetry, Sampson et al. (2010) identify a CFTR corrector that interacts directly with the CFTR domain affected by the F508del mutation.",

author = "DN Sheppard",

note = "Publisher: Elsevier Ltd Other: Commentary",

year = "2011",

month = feb,

doi = "10.1016/j.chembiol.2011.02.003",

language = "English",

volume = "18",

pages = "145 -- 147",

journal = "Chemistry and Biology",

issn = "1074-5521",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Cystic fibrosis: CFTR correctors to the rescue

AU - Sheppard, DN

N1 - Publisher: Elsevier Ltd Other: Commentary

PY - 2011/2

Y1 - 2011/2

N2 - Cystic fibrosis transmembrane conductance regulator (CFTR) correctors are small molecules that target the most common cause of cystic fibrosis: misfolded F508del-CFTR. Using differential scanning fluorimetry, Sampson et al. (2010) identify a CFTR corrector that interacts directly with the CFTR domain affected by the F508del mutation.

AB - Cystic fibrosis transmembrane conductance regulator (CFTR) correctors are small molecules that target the most common cause of cystic fibrosis: misfolded F508del-CFTR. Using differential scanning fluorimetry, Sampson et al. (2010) identify a CFTR corrector that interacts directly with the CFTR domain affected by the F508del mutation.

U2 - 10.1016/j.chembiol.2011.02.003

DO - 10.1016/j.chembiol.2011.02.003

M3 - Article (Academic Journal)

C2 - 21338913

VL - 18

SP - 145

EP - 147

JO - Chemistry and Biology

JF - Chemistry and Biology

SN - 1074-5521

ER -

Cystic fibrosis: CFTR correctors to the rescue

Abstract

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