Data supporting the regulation of FOXC2 in podocyte dysfunction

Neeta Datta; Sonja Lindfors; Naoyuki Miura; Moin A Saleem; Sanna Lehtonen

doi:10.1016/j.dib.2015.12.051

Data supporting the regulation of FOXC2 in podocyte dysfunction

Neeta Datta, Sonja Lindfors, Naoyuki Miura, Moin A Saleem, Sanna Lehtonen

Bristol Medical School (THS)

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Abstract

This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat glomeruli. It also contains information on the effect of the overexpression of transcription factor FOXC2 on the ratio of F- and G-actin and the expression level of ZO-1 in differentiated human podocytes. The article also shows data on the effect of treatments of differentiated podocytes with various factors associated with obesity and diabetes on the expression level of FOXC2. The detailed interpretation of these data and other aspects of podocyte injury mediated by upregulation of FOXC2 can be found in "Overexpression of transcription factor FOXC2 in cultured human podocytes upregulates injury markers and increases motility [1].

Original language	English
Pages (from-to)	514-20
Number of pages	7
Journal	Data in Brief
Volume	6
DOIs	https://doi.org/10.1016/j.dib.2015.12.051
Publication status	Published - Mar 2016

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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Journal Article

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title = "Data supporting the regulation of FOXC2 in podocyte dysfunction",

abstract = "This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat glomeruli. It also contains information on the effect of the overexpression of transcription factor FOXC2 on the ratio of F- and G-actin and the expression level of ZO-1 in differentiated human podocytes. The article also shows data on the effect of treatments of differentiated podocytes with various factors associated with obesity and diabetes on the expression level of FOXC2. The detailed interpretation of these data and other aspects of podocyte injury mediated by upregulation of FOXC2 can be found in {"}Overexpression of transcription factor FOXC2 in cultured human podocytes upregulates injury markers and increases motility [1].",

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author = "Neeta Datta and Sonja Lindfors and Naoyuki Miura and Saleem, \{Moin A\} and Sanna Lehtonen",

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T1 - Data supporting the regulation of FOXC2 in podocyte dysfunction

AU - Datta, Neeta

AU - Lindfors, Sonja

AU - Miura, Naoyuki

AU - Saleem, Moin A

AU - Lehtonen, Sanna

PY - 2016/3

Y1 - 2016/3

N2 - This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat glomeruli. It also contains information on the effect of the overexpression of transcription factor FOXC2 on the ratio of F- and G-actin and the expression level of ZO-1 in differentiated human podocytes. The article also shows data on the effect of treatments of differentiated podocytes with various factors associated with obesity and diabetes on the expression level of FOXC2. The detailed interpretation of these data and other aspects of podocyte injury mediated by upregulation of FOXC2 can be found in "Overexpression of transcription factor FOXC2 in cultured human podocytes upregulates injury markers and increases motility [1].

AB - This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat glomeruli. It also contains information on the effect of the overexpression of transcription factor FOXC2 on the ratio of F- and G-actin and the expression level of ZO-1 in differentiated human podocytes. The article also shows data on the effect of treatments of differentiated podocytes with various factors associated with obesity and diabetes on the expression level of FOXC2. The detailed interpretation of these data and other aspects of podocyte injury mediated by upregulation of FOXC2 can be found in "Overexpression of transcription factor FOXC2 in cultured human podocytes upregulates injury markers and increases motility [1].

KW - Journal Article

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DO - 10.1016/j.dib.2015.12.051

M3 - Article (Academic Journal)

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SN - 2352-3409

VL - 6

SP - 514

EP - 520

JO - Data in Brief

JF - Data in Brief

ER -

Data supporting the regulation of FOXC2 in podocyte dysfunction

Abstract

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