Dearomatising cyclisations of lithiated N-benzylbenzamides

Anjum Ahmed, Jonathan Clayden*, Samreen A. Yasin

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

59 Citations (Scopus)

Abstract

On treatment with Bu(t)Li in the presence of HMPA, N-benzylbenzamides undergo anionic cyclisation with dearomatisation to give an extended amide enolate which reacts with electrophiles to yield bicyclic cyclohexadiene derivatives.

Original languageEnglish
Pages (from-to)231-232
Number of pages2
JournalChemical Communications
Issue number3
DOIs
Publication statusPublished - 7 Feb 1999

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