Deep brain stimulation relieves refractory hypertension

N Patel; S Javed; S Khan; M Papouchado; AL Malizia; AE Pickering; JFR Paton

doi:10.1212/WNL.0b013e3182088108

Deep brain stimulation relieves refractory hypertension

N Patel, S Javed, S Khan, M Papouchado, AL Malizia, AE Pickering, JFR Paton

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

Increased activity of the sympathoadrenal system plays a major role in the pathogenesis of essential hypertension and end organ damage.1,2 Recent effective antihypertensive strategies have manipulated autonomic nervous control mechanisms including renal nerve ablation.1 Here, we present the first patient in whom refractory hypertension was controlled chronically with deep brain stimulation (DBS) of the ventrolateral periaqueductal gray (PAG)/periventricular gray (PVG) as a primary response and not secondary to associated pathologic changes.

Translated title of the contribution	Deep brain stimulation relieves refractory hypertension
Original language	English
Pages (from-to)	405 - 407
Number of pages	2
Journal	Neurology
Volume	76
DOIs	https://doi.org/10.1212/WNL.0b013e3182088108
Publication status	Published - Jan 2011

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title = "Deep brain stimulation relieves refractory hypertension",

abstract = "Increased activity of the sympathoadrenal system plays a major role in the pathogenesis of essential hypertension and end organ damage.1,2 Recent effective antihypertensive strategies have manipulated autonomic nervous control mechanisms including renal nerve ablation.1 Here, we present the first patient in whom refractory hypertension was controlled chronically with deep brain stimulation (DBS) of the ventrolateral periaqueductal gray (PAG)/periventricular gray (PVG) as a primary response and not secondary to associated pathologic changes.",

author = "N Patel and S Javed and S Khan and M Papouchado and AL Malizia and AE Pickering and JFR Paton",

year = "2011",

month = jan,

doi = "10.1212/WNL.0b013e3182088108",

language = "English",

volume = "76",

pages = "405 -- 407",

journal = "Neurology",

issn = "1526-632X",

publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - Deep brain stimulation relieves refractory hypertension

AU - Patel, N

AU - Javed, S

AU - Khan, S

AU - Papouchado, M

AU - Malizia, AL

AU - Pickering, AE

AU - Paton, JFR

PY - 2011/1

Y1 - 2011/1

N2 - Increased activity of the sympathoadrenal system plays a major role in the pathogenesis of essential hypertension and end organ damage.1,2 Recent effective antihypertensive strategies have manipulated autonomic nervous control mechanisms including renal nerve ablation.1 Here, we present the first patient in whom refractory hypertension was controlled chronically with deep brain stimulation (DBS) of the ventrolateral periaqueductal gray (PAG)/periventricular gray (PVG) as a primary response and not secondary to associated pathologic changes.

AB - Increased activity of the sympathoadrenal system plays a major role in the pathogenesis of essential hypertension and end organ damage.1,2 Recent effective antihypertensive strategies have manipulated autonomic nervous control mechanisms including renal nerve ablation.1 Here, we present the first patient in whom refractory hypertension was controlled chronically with deep brain stimulation (DBS) of the ventrolateral periaqueductal gray (PAG)/periventricular gray (PVG) as a primary response and not secondary to associated pathologic changes.

U2 - 10.1212/WNL.0b013e3182088108

DO - 10.1212/WNL.0b013e3182088108

M3 - Article (Academic Journal)

C2 - 21263142

SN - 1526-632X

VL - 76

SP - 405

EP - 407

JO - Neurology

JF - Neurology

ER -

Deep brain stimulation relieves refractory hypertension

Abstract

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