Deep brain stimulation relieves refractory hypertension

N Patel, S Javed, S Khan, M Papouchado, AL Malizia, AE Pickering, JFR Paton

Research output: Contribution to journalArticle (Academic Journal)peer-review

48 Citations (Scopus)

Abstract

Increased activity of the sympathoadrenal system plays a major role in the pathogenesis of essential hypertension and end organ damage.1,2 Recent effective antihypertensive strategies have manipulated autonomic nervous control mechanisms including renal nerve ablation.1 Here, we present the first patient in whom refractory hypertension was controlled chronically with deep brain stimulation (DBS) of the ventrolateral periaqueductal gray (PAG)/periventricular gray (PVG) as a primary response and not secondary to associated pathologic changes.
Translated title of the contributionDeep brain stimulation relieves refractory hypertension
Original languageEnglish
Pages (from-to)405 - 407
Number of pages2
JournalNeurology
Volume76
DOIs
Publication statusPublished - Jan 2011

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