Projects per year
Objectives Around 1% of patients who have a hip replacement have deep prosthetic joint infection (PJI) afterwards. PJI is often treated with antibiotics plus a single revision operation (1-stage revision), or antibiotics plus a 2-stage revision process involving more than 1 operation. This study aimed to characterise the impact and experience of PJI and treatment on patients, including comparison of 1-stage with 2-stage revision treatment.
Design Qualitative semistructured interviews with patients who had undergone surgical revision treatment for PJI. Patients were interviewed between 2 weeks and 12 months postdischarge. Data were audio-recorded, transcribed, anonymised and analysed using a thematic approach, with 20% of transcripts double-coded.
Setting Patients from 5 National Health Service (NHS) orthopaedic departments treating PJI in England and Wales were interviewed in their homes (n=18) or at hospital (n=1).
Participants 19 patients participated (12 men, 7 women, age range 56–88 years, mean age 73.2 years).
Results Participants reported receiving between 1 and 15 revision operations after their primary joint replacement. Analysis indicated that participants made sense of their experience through reference to 3 key phases: the period of symptom onset, the treatment period and protracted recovery after treatment. By conceptualising their experience in this way, and through themes that emerged in these periods, they conveyed the ordeal that PJI represented. Finally, in light of the challenges of PJI, they described the need for support in all of these phases. 2-stage revision had greater impact on participants’ mobility, and further burdens associated with additional complications.
Conclusions Deep PJI impacted on all aspects of patients’ lives. 2-stage revision had greater impact than 1-stage revision on participants’ well-being because the time in between revision procedures meant long periods of immobility and related psychological distress. Participants expressed a need for more psychological and rehabilitative support during treatment and long-term recovery.
- Centre for Surgical Research
- Joint prosthesis
- Surgical revision
- Qualitative research
NIHR Programme Grants for Applied Research: RP-PG-1210-12005 Application Title: Infection after total joint replacement
1/02/14 → 31/05/20
Craddock, I. J., Coyle, D. T., Flach, P. A., Kaleshi, D., Mirmehdi, M., Piechocki, R. J., Stark, B. H., Ascione, R., Ashburn, A. M., Burnett, M. E., Damen, D., Gooberman-Hill, R. J. S., Harwin, W. S., Hilton, G., Holderbaum, W., Holley, A. P., Manchester, V. A., Meller, B. J., Stack, E. & Gilchrist, I. D.
1/10/13 → 30/09/18
Project: Research, Parent