There is general agreement that atherosclerotic plaque rupture is a major clinical problem and that finding ways to prevent it would be greatly facilitated by an animal model of plaque rupture. The article seeks to clarify and define the terms used in descriptions of disrupted atherosclerotic plaques, and then to apply these to murine models in order to assess their similarities to and differences from human ruptured lesions.
|Translated title of the contribution||Defining and defending murine models of plaque rupture|
|Pages (from-to)||973 - 977|
|Number of pages||5|
|Journal||Arteriosclerosis, Thrombosis, and Vascular Biology|
|Publication status||Published - Apr 2007|