Defining and defending murine models of plaque rupture

CL Jackson

Research output: Contribution to journalArticle (Academic Journal)peer-review

31 Citations (Scopus)


There is general agreement that atherosclerotic plaque rupture is a major clinical problem and that finding ways to prevent it would be greatly facilitated by an animal model of plaque rupture. The article seeks to clarify and define the terms used in descriptions of disrupted atherosclerotic plaques, and then to apply these to murine models in order to assess their similarities to and differences from human ruptured lesions.
Translated title of the contributionDefining and defending murine models of plaque rupture
Original languageEnglish
Pages (from-to)973 - 977
Number of pages5
JournalArteriosclerosis, Thrombosis, and Vascular Biology
Volume27 (4)
Publication statusPublished - Apr 2007

Bibliographical note

Publisher: Lippincott, Williams & Wilkins


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