Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations

Mattia Lunardi; Yves Louvard; Thierry Lefèvre; Goran Stankovic; Francesco Burzotta; Ghassan S Kassab; Jens Flensted Lassen; Olivier Darremont; Scot Garg; Bon-Kwon Koo; Niels Ramsing Holm; Thomas W Johnson; Manuel Pan; Yiannis S Chatzizisis; Adrian P Banning; Alaide Chieffo; Dariusz Dudek; David Hildick-Smith; Jérome Garot; Timothy D Henry; George Dangas; Gregg Stone; Mitchell W Krucoff; Donald Cutlip; Roxana Mehran; William Wijns; Faisal Sharif; Patrick W Serruys; Yoshinobu Onuma

doi:10.4244/EIJ-E-22-00018

Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations

Mattia Lunardi, Yves Louvard, Thierry Lefèvre, Goran Stankovic, Francesco Burzotta, Ghassan S Kassab, Jens Flensted Lassen, Olivier Darremont, Scot Garg, Bon-Kwon Koo, Niels Ramsing Holm, Thomas W Johnson, Manuel Pan, Yiannis S Chatzizisis, Adrian P Banning, Alaide Chieffo, Dariusz Dudek, David Hildick-Smith, Jérome Garot, Timothy D HenryGeorge Dangas, Gregg Stone, Mitchell W Krucoff, Donald Cutlip, Roxana Mehran, William Wijns, Faisal Sharif, Patrick W Serruys, Yoshinobu Onuma

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

The Bifurcation Academic Research Consortium (Bif-ARC) project originated from the need to overcome the paucity of standardization and comparability between studies involving bifurcation coronary lesions. This document is the result of a collaborative effort between academic research organizations and the most renowned interventional cardiology societies focused on bifurcation lesions in Europe, the United States, and Asia. This consensus provides standardized deﬁnitions for bifurcation lesions; the criteria to judge the side branch relevance; the procedural, mechanistic, and clinical endpoints for every type of bifurcation study; and the follow-up methods. Considering the complexity of bifurcation lesions and their evaluation, detailed instructions and technical aspects for site and core laboratory analysis of bifurcation lesions are also reported. The recommendations included within this consensus will facilitate pooled analyses and the effective comparison of data in the future, improving the clinical relevance of trials in bifurcation lesions, and the quality of care in this subset of patients.

Original language	English
Journal	Eurointervention
Early online date	18 May 2022
DOIs	https://doi.org/10.4244/EIJ-E-22-00018
Publication status	E-pub ahead of print - 18 May 2022

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This is the final published version of the article (version of record). It first appeared online via EuroIntervention at https://eurointervention.pcronline.com/article/definitions-and-standardized-endpoints-for-treatment-of-coronary-bifurcations . Please refer to any applicable terms of use of the publisher.
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Lunardi, M., Louvard, Y., Lefèvre, T., Stankovic, G., Burzotta, F., Kassab, G. S., Lassen, J. F., Darremont, O., Garg, S., Koo, B.-K., Holm, N. R., Johnson, T. W., Pan, M., Chatzizisis, Y. S., Banning, A. P., Chieffo, A., Dudek, D., Hildick-Smith, D., Garot, J., ... Onuma, Y. (2022). Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations. Eurointervention. Advance online publication. https://doi.org/10.4244/EIJ-E-22-00018

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title = "Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations",

abstract = "The Bifurcation Academic Research Consortium (Bif-ARC) project originated from the need to overcome the paucity of standardization and comparability between studies involving bifurcation coronary lesions. This document is the result of a collaborative effort between academic research organizations and the most renowned interventional cardiology societies focused on bifurcation lesions in Europe, the United States, and Asia. This consensus provides standardized deﬁnitions for bifurcation lesions; the criteria to judge the side branch relevance; the procedural, mechanistic, and clinical endpoints for every type of bifurcation study; and the follow-up methods. Considering the complexity of bifurcation lesions and their evaluation, detailed instructions and technical aspects for site and core laboratory analysis of bifurcation lesions are also reported. The recommendations included within this consensus will facilitate pooled analyses and the effective comparison of data in the future, improving the clinical relevance of trials in bifurcation lesions, and the quality of care in this subset of patients.",

author = "Mattia Lunardi and Yves Louvard and Thierry Lef{\`e}vre and Goran Stankovic and Francesco Burzotta and Kassab, {Ghassan S} and Lassen, {Jens Flensted} and Olivier Darremont and Scot Garg and Bon-Kwon Koo and Holm, {Niels Ramsing} and Johnson, {Thomas W} and Manuel Pan and Chatzizisis, {Yiannis S} and Banning, {Adrian P} and Alaide Chieffo and Dariusz Dudek and David Hildick-Smith and J{\'e}rome Garot and Henry, {Timothy D} and George Dangas and Gregg Stone and Krucoff, {Mitchell W} and Donald Cutlip and Roxana Mehran and William Wijns and Faisal Sharif and Serruys, {Patrick W} and Yoshinobu Onuma",

year = "2022",

month = may,

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doi = "10.4244/EIJ-E-22-00018",

language = "English",

journal = "Eurointervention",

issn = "1774-024X",

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Lunardi, M, Louvard, Y, Lefèvre, T, Stankovic, G, Burzotta, F, Kassab, GS, Lassen, JF, Darremont, O, Garg, S, Koo, B-K, Holm, NR, Johnson, TW, Pan, M, Chatzizisis, YS, Banning, AP, Chieffo, A, Dudek, D, Hildick-Smith, D, Garot, J, Henry, TD, Dangas, G, Stone, G, Krucoff, MW, Cutlip, D, Mehran, R, Wijns, W, Sharif, F, Serruys, PW & Onuma, Y 2022, 'Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations', Eurointervention. https://doi.org/10.4244/EIJ-E-22-00018

TY - JOUR

T1 - Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations

AU - Lunardi, Mattia

AU - Louvard, Yves

AU - Lefèvre, Thierry

AU - Stankovic, Goran

AU - Burzotta, Francesco

AU - Kassab, Ghassan S

AU - Lassen, Jens Flensted

AU - Darremont, Olivier

AU - Garg, Scot

AU - Koo, Bon-Kwon

AU - Holm, Niels Ramsing

AU - Johnson, Thomas W

AU - Pan, Manuel

AU - Chatzizisis, Yiannis S

AU - Banning, Adrian P

AU - Chieffo, Alaide

AU - Dudek, Dariusz

AU - Hildick-Smith, David

AU - Garot, Jérome

AU - Henry, Timothy D

AU - Dangas, George

AU - Stone, Gregg

AU - Krucoff, Mitchell W

AU - Cutlip, Donald

AU - Mehran, Roxana

AU - Wijns, William

AU - Sharif, Faisal

AU - Serruys, Patrick W

AU - Onuma, Yoshinobu

PY - 2022/5/18

Y1 - 2022/5/18

N2 - The Bifurcation Academic Research Consortium (Bif-ARC) project originated from the need to overcome the paucity of standardization and comparability between studies involving bifurcation coronary lesions. This document is the result of a collaborative effort between academic research organizations and the most renowned interventional cardiology societies focused on bifurcation lesions in Europe, the United States, and Asia. This consensus provides standardized deﬁnitions for bifurcation lesions; the criteria to judge the side branch relevance; the procedural, mechanistic, and clinical endpoints for every type of bifurcation study; and the follow-up methods. Considering the complexity of bifurcation lesions and their evaluation, detailed instructions and technical aspects for site and core laboratory analysis of bifurcation lesions are also reported. The recommendations included within this consensus will facilitate pooled analyses and the effective comparison of data in the future, improving the clinical relevance of trials in bifurcation lesions, and the quality of care in this subset of patients.

AB - The Bifurcation Academic Research Consortium (Bif-ARC) project originated from the need to overcome the paucity of standardization and comparability between studies involving bifurcation coronary lesions. This document is the result of a collaborative effort between academic research organizations and the most renowned interventional cardiology societies focused on bifurcation lesions in Europe, the United States, and Asia. This consensus provides standardized deﬁnitions for bifurcation lesions; the criteria to judge the side branch relevance; the procedural, mechanistic, and clinical endpoints for every type of bifurcation study; and the follow-up methods. Considering the complexity of bifurcation lesions and their evaluation, detailed instructions and technical aspects for site and core laboratory analysis of bifurcation lesions are also reported. The recommendations included within this consensus will facilitate pooled analyses and the effective comparison of data in the future, improving the clinical relevance of trials in bifurcation lesions, and the quality of care in this subset of patients.

U2 - 10.4244/EIJ-E-22-00018

DO - 10.4244/EIJ-E-22-00018

M3 - Article (Academic Journal)

C2 - 35583108

SN - 1774-024X

JO - Eurointervention

JF - Eurointervention

ER -

Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations

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