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Abstract
This paper reports a negligible-cost, open-source method for the rapid prototyping of microfluidic systems in polydimethylsiloxane (PDMS) using a 3D-printed library of click-and-connect microchannel scaffolds. In conjunction with a simple thermal bonding process, these single-extrusion thermoplastic scaffolds are designed and used to quickly configure microfluidic system negatives, for use as master molds in the fabrication of PDMS microfluidics demonstrated herein. With this technique, a 5000-piece library of mix-and-match interconnecting channel scaffolds can be printed, with a 100 µm channel width, for ~$0.50. This simple yet innovative approach could help to lower the economic barriers for lab-on-a-chip fabrication.
Original language | English |
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Title of host publication | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
Publisher | Chemical and Biological Microsystems Society |
Pages | 428-429 |
Number of pages | 2 |
ISBN (Electronic) | 9781733419017 |
Publication status | Published - 2020 |
Event | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online Duration: 4 Oct 2020 → 9 Oct 2020 |
Publication series
Name | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
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Conference
Conference | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 |
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City | Virtual, Online |
Period | 4/10/20 → 9/10/20 |
Bibliographical note
Funding Information:Research supported via the Engineering and Physical Sciences Research Council (EPSRC) & Global Challenges Research Fund (GCRF) via the BristolBridge program (EP/M027546/1) with additional support from EPSRC, grant reference EP/R032696/1. Thanks also to Dr Annela Seddon, University of Bristol, for her support.
Publisher Copyright:
© 2020 CBMS-0001
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
Keywords
- 3D-Printing
- Low-Cost Microfluidics
- Polydimethylsiloxane
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Bristol Bridge EP/M027546/1 DA Investigators
Homer, M. E. (Principal Investigator)
1/08/16 → …
Project: Research, Parent
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ProtoTwinning: Digital Physical Twinning in Product Development EP/R032696/1
Hicks, B. J. (Principal Investigator), Nassehi, A. (Co-Investigator) & Snider, C. M. (Co-Investigator)
1/08/18 → 31/07/23
Project: Research