Design, fabrication and initial evaluation of a novel hybrid bioextrusion system for tissue engineering applications

Fengyuan Liu, Sri Hinduja, Paulo Bartolo*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

A novel hybrid biomanufacturing system, called Plasma-assisted Bioextrusion System (PABS), has been developed to produce multi-material and functional graded scaffolds for tissue engineering applications. It combines pressure-assisted extrusion heads, screw-assisted extrusion heads and plasma jets, allowing surface of printed scaffolds matching the characteristics of the surrounding tissue. This paper explores this system to produce PCL and PCL/CNT scaffolds for bone applications. Processing conditions were optimized in terms of deposition velocity, screw rotational velocity and the effect of these parameters on the morphological and mechanical properties of produced scaffolds assessed.
Original languageEnglish
Pages (from-to)213-218
JournalProcedia CIRP
Volume65
Publication statusPublished - 2017

Keywords

  • hybrid system
  • tissue engineering
  • Scaffolding

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