Development of the FAST-M maternal sepsis care bundle for use in low resource settings: a modified Delphi process

David Lissauer, James Cheshire, Catherine Dunlop, Fatima Taki, Amie Wilson, Jeffery Smith, Ron Daniels, Niranjan Kissoon, Address Malata, Thomson Chirwa, Victoria Lwesha, Chisale Mhango, Edward Mhango, Charles Makwenda, Lumbani Banda, Laura Munthali, Bejoy Nambiar, Julia Hussein, Helen M Williams, Adam J DevallIoannis Gallos, Abi Merriel, Mercedes Bonet, Joao Paulo Souza, Arri Coomarasamy

Research output: Contribution to journalArticle (Academic Journal)peer-review

8 Citations (Scopus)
127 Downloads (Pure)


Objective: To develop a sepsis care bundle for the initial management of maternal sepsis in low resource settings.
Design: Modified Delphi process.
Setting: Participants from 34 countries.
Population: Healthcare practitioners working in low resource settings (n=143; 34 countries), members of an expert panel (n=11) and consultation with the World Health Organization Global Maternal and Neonatal Sepsis Initiative technical working group.
Methods: We reviewed the literature to identify all potential interventions and practices around the initial management of sepsis that could be bundled together. A modified Delphi process, using an online questionnaire and in-person meetings, was then undertaken to gain consensus on bundle items. Participants ranked potential bundle items in terms of perceived importance and feasibility, considering its use in both hospitals and health centres. Findings from the healthcare practitioners were then triangulated with those of the experts.
Main outcome measure: Consensus on bundle items.
Results: Consensus was reached after three consultation rounds, with the same items deemed most important and feasible by both the healthcare practitioners and expert panel. Final bundle items selected were: i) Fluids, ii) Antibiotics, iii) Source identification and control, iv) Transfer (to appropriate higher-level care) and v) Monitoring (of both mother and neonate as appropriate). The bundle was given the acronym “FAST-M”.
Conclusion: A clinically relevant maternal sepsis care bundle for low resource settings has been developed by international consensus.
Original languageEnglish
Number of pages8
JournalBJOG: An International Journal of Obstetrics and Gynaecology
Publication statusAccepted/In press - 26 Oct 2019


  • Maternal sepsis
  • low resource setting
  • care bundle
  • Delphi process


Dive into the research topics of 'Development of the FAST-M maternal sepsis care bundle for use in low resource settings: a modified Delphi process'. Together they form a unique fingerprint.

Cite this