Projects per year
Abstract
CF3-substituted vinyl diphenylsulfonium triflate is an effective annulation reagent for the formation of alpha-CF3 substituted, epoxide-fused heterocycles (pyrrolidines, piperidines, and tetrahydrofurans). This simple method affords a variety of valuable heterocyclic building blocks in a highly diastereoselective manner (dr>20:1).
Original language | English |
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Pages (from-to) | 6370-6373 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 14 |
Issue number | 24 |
DOIs | |
Publication status | Published - 21 Dec 2012 |
Keywords
- VINYL SULFONIUM SALTS
- MEDICINAL CHEMISTRY
- CONVENIENT METHOD
- STRAIGHTFORWARD SYNTHESIS
- ASYMMETRIC-SYNTHESIS
- ALPHA-IMIDOSTYRENES
- EFFICIENT SYNTHESIS
- TANDEM REACTIONS
- FLUORINE
- TRIFLATE
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Dive into the research topics of 'Diastereoselective Synthesis of CF3-Substituted, Epoxide-Fused Heterocycles with beta-(Trifluoromethyl)vinylsulfonium Salts'. Together they form a unique fingerprint.Projects
- 2 Finished
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GENERAL AND CONVERGENT STRATEGY FOR ASYMMETRIC SYNTHESIS
Aggarwal, V. K. (Principal Investigator)
1/10/07 → 1/04/13
Project: Research
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NEW ASSYMETRIC REACTIONS AND THEIR APPLICATION IN TOTAL SYNTHESIS
Aggarwal, V. K. (Principal Investigator)
1/10/05 → 1/10/10
Project: Research