Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000

Samantha Lang; Sarah Schimansky; Rhona Beynon; Christopher Penfold; Amy Davies; Andrea Waylen; Steven Thomas; Miranda Pring; Michael Pawlita; Tim Waterboer; Andrew R. Ness

doi:10.1002/hed.25660

Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000

Samantha Lang^*, Sarah Schimansky, Rhona Beynon, Christopher Penfold, Amy Davies, Andrea Waylen, Steven Thomas, Miranda Pring, Michael Pawlita, Tim Waterboer, Andrew R. Ness

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

8 Citations (Scopus)

156 Downloads (Pure)

Abstract

BACKGROUND: The association between diet and head and neck cancer (HNC) survival is unclear.

METHODS: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.

RESULTS: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).

CONCLUSIONS: Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.

Original language	English
Pages (from-to)	2074-2084
Number of pages	11
Journal	Head and Neck
Volume	41
Issue number	7
Early online date	30 Jan 2019
DOIs	https://doi.org/10.1002/hed.25660
Publication status	Published - 1 Jul 2019

Bibliographical note

Research Groups and Themes

ICEP

Keywords

deep-fried food
fruit
head and neck cancers
survival
vegetables

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/hed.25660

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title = "Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000",

abstract = "BACKGROUND: The association between diet and head and neck cancer (HNC) survival is unclear.METHODS: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.RESULTS: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).CONCLUSIONS: Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.",

keywords = "deep-fried food, fruit, head and neck cancers, survival, vegetables",

author = "Samantha Lang and Sarah Schimansky and Rhona Beynon and Christopher Penfold and Amy Davies and Andrea Waylen and Steven Thomas and Miranda Pring and Michael Pawlita and Tim Waterboer and Ness, {Andrew R.}",

note = "{\textcopyright} 2019 Wiley Periodicals, Inc.",

year = "2019",

month = jul,

day = "1",

doi = "10.1002/hed.25660",

language = "English",

volume = "41",

pages = "2074--2084",

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TY - JOUR

T1 - Dietary behaviors and survival in people with head and neck cancer

T2 - Results from Head and Neck 5000

AU - Lang, Samantha

AU - Schimansky, Sarah

AU - Beynon, Rhona

AU - Penfold, Christopher

AU - Davies, Amy

AU - Waylen, Andrea

AU - Thomas, Steven

AU - Pring, Miranda

AU - Pawlita, Michael

AU - Waterboer, Tim

AU - Ness, Andrew R.

PY - 2019/7/1

Y1 - 2019/7/1

N2 - BACKGROUND: The association between diet and head and neck cancer (HNC) survival is unclear.METHODS: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.RESULTS: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).CONCLUSIONS: Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.

AB - BACKGROUND: The association between diet and head and neck cancer (HNC) survival is unclear.METHODS: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.RESULTS: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).CONCLUSIONS: Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.

KW - deep-fried food

KW - fruit

KW - head and neck cancers

KW - survival

KW - vegetables

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U2 - 10.1002/hed.25660

DO - 10.1002/hed.25660

M3 - Article (Academic Journal)

C2 - 30698303

SN - 1043-3074

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SP - 2074

EP - 2084

JO - Head and Neck

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IS - 7

ER -

Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000

Abstract

Bibliographical note

Research Groups and Themes

Keywords

UN SDGs

Access to Document

Handle.net

Other files and links

Fingerprint

NIHR BRC Nutrition

Dr Miranda Pring

Cite this

Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000

Abstract

Bibliographical note

Research Groups and Themes

Keywords

UN SDGs

Access to Document

Handle.net

Other files and links

Fingerprint

Projects

NIHR BRC Nutrition

Profiles

Dr Miranda Pring

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