Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000

Samantha Lang; Sarah Schimansky; Rhona Beynon; Christopher Penfold; Amy Davies; Andrea Waylen; Steven Thomas; Miranda Pring; Michael Pawlita; Tim Waterboer; Andrew R. Ness

doi:10.1002/hed.25660

Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000

Samantha Lang^*, Sarah Schimansky, Rhona Beynon, Christopher Penfold, Amy Davies, Andrea Waylen, Steven Thomas, Miranda Pring, Michael Pawlita, Tim Waterboer, Andrew R. Ness

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal)

1 Citation (Scopus)

88 Downloads (Pure)

Abstract

BACKGROUND: The association between diet and head and neck cancer (HNC) survival is unclear.

METHODS: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.

RESULTS: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).

CONCLUSIONS: Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.

Original language	English
Pages (from-to)	2074-2084
Number of pages	11
Journal	Head and Neck
Volume	41
Issue number	7
Early online date	30 Jan 2019
DOIs	https://doi.org/10.1002/hed.25660
Publication status	Published - 1 Jul 2019

Bibliographical note

Structured keywords

ICEP

Keywords

deep-fried food
fruit
head and neck cancers
survival
vegetables

Access to Document

10.1002/hed.25660

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Projects

1 Active

NIHR BRC Nutrition

Ness, A. R.

1/04/17 → 31/03/22

Project: Research, Parent

Profiles

Professor Andy R Ness

Andy.Ness@bristol.ac.uk

Bristol Dental School - Professor of Epidemiology
Bristol Population Health Science Institute
Cancer

Person: Academic , Member

Dr Miranda Pring

Miranda.Pring@bristol.ac.uk

Bristol Dental School - Consultant Senior Lecturer in Oral Maxillofacial Pathology

Person: Academic

Professor Steve J Thomas

Steve.Thomas@bristol.ac.uk

Cancer
Bristol Dental School - Professor in Oral and Maxillofacial Surgery

Person: Academic , Member

Cite this

Lang, S., Schimansky, S., Beynon, R., Penfold, C., Davies, A., Waylen, A., Thomas, S., Pring, M., Pawlita, M., Waterboer, T., & Ness, A. R. (2019). Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000. Head and Neck, 41(7), 2074-2084. https://doi.org/10.1002/hed.25660

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abstract = "BACKGROUND: The association between diet and head and neck cancer (HNC) survival is unclear.METHODS: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.RESULTS: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).CONCLUSIONS: Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.",

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Dietary behaviors and survival in people with head and neck cancer : Results from Head and Neck 5000. / Lang, Samantha; Schimansky, Sarah; Beynon, Rhona ; Penfold, Christopher ; Davies, Amy ; Waylen, Andrea ; Thomas, Steven ; Pring, Miranda; Pawlita, Michael; Waterboer, Tim; Ness, Andrew R.

In: Head and Neck, Vol. 41, No. 7, 01.07.2019, p. 2074-2084.

Research output: Contribution to journal › Article (Academic Journal)

TY - JOUR

T1 - Dietary behaviors and survival in people with head and neck cancer

T2 - Results from Head and Neck 5000

AU - Lang, Samantha

AU - Schimansky, Sarah

AU - Beynon, Rhona

AU - Penfold, Christopher

AU - Davies, Amy

AU - Waylen, Andrea

AU - Thomas, Steven

AU - Pring, Miranda

AU - Pawlita, Michael

AU - Waterboer, Tim

AU - Ness, Andrew R.

PY - 2019/7/1

Y1 - 2019/7/1

N2 - BACKGROUND: The association between diet and head and neck cancer (HNC) survival is unclear.METHODS: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.RESULTS: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).CONCLUSIONS: Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.

AB - BACKGROUND: The association between diet and head and neck cancer (HNC) survival is unclear.METHODS: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.RESULTS: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).CONCLUSIONS: Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.

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