Do Mass Spectrometry-Derived Metabolomics Improve the Prediction of Pregnancy-Related Disorders? Findings from a UK Birth Cohort with Independent Validation

Nancy S Mcbride, Paul D Yousefi, Kurt Taylor, Ulla Sovio, Matthew J Suderman, Caroline L Relton, Tiffany Yang, Bo Hou, Yassaman Vafai, Gordon C S Smith, Deborah A Lawlor

Research output: Contribution to journalArticle (Academic Journal)peer-review

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Original languageEnglish
Article number530
JournalMetabolites
Volume11
Issue number8
DOIs
Publication statusPublished - 10 Aug 2021

Bibliographical note

Funding Information:
Funding: This work was supported by the National Institute for Health Research (NIHR) Biomedical Centre at the University Hospitals Bristol NHS Foundation Trust and the University of Bristol, which funds N.M.’s PhD studentship; the US National Institute of Health (R01 DK10324); and the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007– 2013)/ERC grant agreement no 669545. Core funding for Born in Bradford (BiB) was funded by the Wellcome Trust (WT101597MA), a joint grant from the UK Medical Research Council (MRC) and the UK Economic and Social Science Research Council (ESRC) (MR/N024397/1), the British Heart Foundation (CS/16/4/32482) and the NIHR under its Collaboration for Applied Health Research and Care (CLAHRC) for Yorkshire and Humber and the Clinical Research Network (CRN). This study received funding from the National Institute of Health Research (RP-PG-0407-10452) and the Medical Research Council UK (MR/L002477/1). The work of U.S. was funded by the NIHR Cambridge Biomedical Research Centre (Women’s Health theme). K.T is supported by a British Heart Foundation Doctoral Training Program (FS/17/60/33474). CR is supported by the MRC Integrative Epidemiology Unit at the University of Bristol (MC_UU_00011/5/MRC). The funders did not have any role in the design, analysis or preparation of the manuscript for publication. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, the NIHR, the Department of Health and Social Care or any of the funders listed above.

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© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

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