Abstract
Patients with end-stage renal disease have a high risk of dying from cardiovascular disease that cannot be explained solely by traditional cardiovascular disease risk factors. Hesse et al. suggest that dysfunctional high-density lipoprotein cholesterol generated in patients with end-stage renal disease causes endothelial glycocalyx degradation. Glycocalyx degradation may represent one of the earliest insults leading to atheroma formation, and so this work suggests a novel link between renal failure and cardiovascular disease.
Original language | English |
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Pages (from-to) | 450-452 |
Number of pages | 3 |
Journal | Kidney International |
Volume | 97 |
Issue number | 3 |
Early online date | 19 Feb 2020 |
DOIs |
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Publication status | Published - Mar 2020 |