Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial

Lorenz Räber; Henning Kelbæk; Miodrag Ostojic; Miodrag Ostoijc; Andreas Baumbach; Dik Heg; David Tüller; Clemens von Birgelen; Marco Roffi; Aris Moschovitis; Ahmed A Khattab; Peter Wenaweser; Robert Bonvini; Giovanni Pedrazzini; Ran Kornowski; Klaus Weber; Sven Trelle; Thomas F Lüscher; Masanori Taniwaki; Christian M Matter; Bernhard Meier; Peter Jüni; Stephan Windecker; COMFORTABLE AMI Trial Investigators

doi:10.1001/jama.2012.10065

Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial

Lorenz Räber, Henning Kelbæk, Miodrag Ostojic, Miodrag Ostoijc, Andreas Baumbach, Dik Heg, David Tüller, Clemens von Birgelen, Marco Roffi, Aris Moschovitis, Ahmed A Khattab, Peter Wenaweser, Robert Bonvini, Giovanni Pedrazzini, Ran Kornowski, Klaus Weber, Sven Trelle, Thomas F Lüscher, Masanori Taniwaki, Christian M MatterBernhard Meier, Peter Jüni, Stephan Windecker, COMFORTABLE AMI Trial Investigators

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

268 Citations (Scopus)

Abstract

The efficacy and safety of drug-eluting stents compared with bare-metal stents remains controversial in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).

Original language	English
Pages (from-to)	777-787
Number of pages	11
Journal	JAMA - Journal of the American Medical Association
Volume	308
Issue number	8
DOIs	https://doi.org/10.1001/jama.2012.10065
Publication status	Published - 22 Aug 2012

Keywords

Absorbable Implants
Aged
Drug-Eluting Stents
Female
Humans
Male
Metals
Middle Aged
Myocardial Infarction
Myocardial Ischemia
Myocardial Reperfusion
Myocardial Revascularization
Polymers
Prospective Studies
Recurrence
Risk
Single-Blind Method
Sirolimus
Treatment Outcome

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Räber, L., Kelbæk, H., Ostojic, M., Ostoijc, M., Baumbach, A., Heg, D., Tüller, D., von Birgelen, C., Roffi, M., Moschovitis, A., Khattab, A. A., Wenaweser, P., Bonvini, R., Pedrazzini, G., Kornowski, R., Weber, K., Trelle, S., Lüscher, T. F., Taniwaki, M., ... COMFORTABLE AMI Trial Investigators (2012). Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial. JAMA - Journal of the American Medical Association, 308(8), 777-787. https://doi.org/10.1001/jama.2012.10065

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title = "Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial",

abstract = "The efficacy and safety of drug-eluting stents compared with bare-metal stents remains controversial in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).",

keywords = "Absorbable Implants, Aged, Drug-Eluting Stents, Female, Humans, Male, Metals, Middle Aged, Myocardial Infarction, Myocardial Ischemia, Myocardial Reperfusion, Myocardial Revascularization, Polymers, Prospective Studies, Recurrence, Risk, Single-Blind Method, Sirolimus, Treatment Outcome",

author = "Lorenz R{\"a}ber and Henning Kelb{\ae}k and Miodrag Ostojic and Miodrag Ostoijc and Andreas Baumbach and Dik Heg and David T{\"u}ller and \{von Birgelen\}, Clemens and Marco Roffi and Aris Moschovitis and Khattab, \{Ahmed A\} and Peter Wenaweser and Robert Bonvini and Giovanni Pedrazzini and Ran Kornowski and Klaus Weber and Sven Trelle and L{\"u}scher, \{Thomas F\} and Masanori Taniwaki and Matter, \{Christian M\} and Bernhard Meier and Peter J{\"u}ni and Stephan Windecker and \{COMFORTABLE AMI Trial Investigators\}",

year = "2012",

month = aug,

day = "22",

doi = "10.1001/jama.2012.10065",

language = "English",

volume = "308",

pages = "777--787",

journal = "JAMA - Journal of the American Medical Association",

issn = "0098-7484",

publisher = "American Medical Association",

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Räber, L, Kelbæk, H, Ostojic, M, Ostoijc, M, Baumbach, A, Heg, D, Tüller, D, von Birgelen, C, Roffi, M, Moschovitis, A, Khattab, AA, Wenaweser, P, Bonvini, R, Pedrazzini, G, Kornowski, R, Weber, K, Trelle, S, Lüscher, TF, Taniwaki, M, Matter, CM, Meier, B, Jüni, P, Windecker, S & COMFORTABLE AMI Trial Investigators 2012, 'Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial', JAMA - Journal of the American Medical Association, vol. 308, no. 8, pp. 777-787. https://doi.org/10.1001/jama.2012.10065

Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial. / Räber, Lorenz; Kelbæk, Henning; Ostojic, Miodrag et al.
In: JAMA - Journal of the American Medical Association, Vol. 308, No. 8, 22.08.2012, p. 777-787.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction

T2 - the COMFORTABLE AMI randomized trial

AU - Räber, Lorenz

AU - Kelbæk, Henning

AU - Ostojic, Miodrag

AU - Ostoijc, Miodrag

AU - Baumbach, Andreas

AU - Heg, Dik

AU - Tüller, David

AU - von Birgelen, Clemens

AU - Roffi, Marco

AU - Moschovitis, Aris

AU - Khattab, Ahmed A

AU - Wenaweser, Peter

AU - Bonvini, Robert

AU - Pedrazzini, Giovanni

AU - Kornowski, Ran

AU - Weber, Klaus

AU - Trelle, Sven

AU - Lüscher, Thomas F

AU - Taniwaki, Masanori

AU - Matter, Christian M

AU - Meier, Bernhard

AU - Jüni, Peter

AU - Windecker, Stephan

AU - COMFORTABLE AMI Trial Investigators

PY - 2012/8/22

Y1 - 2012/8/22

N2 - The efficacy and safety of drug-eluting stents compared with bare-metal stents remains controversial in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).

AB - The efficacy and safety of drug-eluting stents compared with bare-metal stents remains controversial in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).

KW - Absorbable Implants

KW - Aged

KW - Drug-Eluting Stents

KW - Female

KW - Humans

KW - Male

KW - Metals

KW - Middle Aged

KW - Myocardial Infarction

KW - Myocardial Ischemia

KW - Myocardial Reperfusion

KW - Myocardial Revascularization

KW - Polymers

KW - Prospective Studies

KW - Recurrence

KW - Risk

KW - Single-Blind Method

KW - Sirolimus

KW - Treatment Outcome

UR - https://www.scopus.com/pages/publications/84865334791

U2 - 10.1001/jama.2012.10065

DO - 10.1001/jama.2012.10065

M3 - Article (Academic Journal)

C2 - 22910755

SN - 0098-7484

VL - 308

SP - 777

EP - 787

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

IS - 8

ER -

Räber L, Kelbæk H, Ostojic M, Ostoijc M, Baumbach A, Heg D et al. Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial. JAMA - Journal of the American Medical Association. 2012 Aug 22;308(8):777-787. doi: 10.1001/jama.2012.10065

Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial

Abstract

Keywords

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