Effect of cardiac compressions and hypothermia treatment on cardiac troponin I in newborns with perinatal asphyxia

Xun Liu; Ela Chakkarapani; Janet Stone; Marianne Thoresen

doi:10.1016/j.resuscitation.2013.07.003

Effect of cardiac compressions and hypothermia treatment on cardiac troponin I in newborns with perinatal asphyxia

Xun Liu, Ela Chakkarapani, Janet Stone, Marianne Thoresen

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

The American Heart Association, the European Resuscitation and the International Liaison Committee issued new neonatal resuscitation guidelines (2010) where therapeutic hypothermia is introduced after hypoxic-ischaemic encephalopathy (HIE) in term infants to prevent brain injury. Our study aimed to investigate whether hypothermia can reduce the release of a cardiac cellular marker, cardiac troponin I (cTnI), in HIE infants compared to normothermia care, if cTnI can be used as a prognostic marker for long term neuro-developmental outcome and if cardiac compression at birth affects the level of cTnI.

Original language	English
Number of pages	6
Journal	Resuscitation
DOIs	https://doi.org/10.1016/j.resuscitation.2013.07.003
Publication status	Published - 12 Jul 2013

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title = "Effect of cardiac compressions and hypothermia treatment on cardiac troponin I in newborns with perinatal asphyxia",

abstract = "The American Heart Association, the European Resuscitation and the International Liaison Committee issued new neonatal resuscitation guidelines (2010) where therapeutic hypothermia is introduced after hypoxic-ischaemic encephalopathy (HIE) in term infants to prevent brain injury. Our study aimed to investigate whether hypothermia can reduce the release of a cardiac cellular marker, cardiac troponin I (cTnI), in HIE infants compared to normothermia care, if cTnI can be used as a prognostic marker for long term neuro-developmental outcome and if cardiac compression at birth affects the level of cTnI.",

author = "Xun Liu and Ela Chakkarapani and Janet Stone and Marianne Thoresen",

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AU - Chakkarapani, Ela

AU - Stone, Janet

AU - Thoresen, Marianne

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AB - The American Heart Association, the European Resuscitation and the International Liaison Committee issued new neonatal resuscitation guidelines (2010) where therapeutic hypothermia is introduced after hypoxic-ischaemic encephalopathy (HIE) in term infants to prevent brain injury. Our study aimed to investigate whether hypothermia can reduce the release of a cardiac cellular marker, cardiac troponin I (cTnI), in HIE infants compared to normothermia care, if cTnI can be used as a prognostic marker for long term neuro-developmental outcome and if cardiac compression at birth affects the level of cTnI.

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DO - 10.1016/j.resuscitation.2013.07.003

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SN - 0300-9572

ER -

Effect of cardiac compressions and hypothermia treatment on cardiac troponin I in newborns with perinatal asphyxia

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