Effect of decellularization protocol of human saphenous veins on cytotoxicity and matrix component

Nadiah Sulaiman, Sandro Satta, Sarah George, Saadeh Suleiman, Raimondo Ascione

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

Rationale for the study: It is proposed that development of arterial-like vascular conduits using decellularised venous extracellular matrix scaffolds seeded with cells are desirable to overcome the problem of early vein graft thrombosis, late vein graft thickening, and artificial grafts infection of autologous, xeno- and artificial graft conduit used for coronary artery bypass surgery. The aim of this study was to compare the effect of different decellularisation protocols on vein matrix components and cytotoxicity on seeded cells.
Original languageEnglish
Pages (from-to)e11-e12
JournalAtherosclerosis
Volume244
Publication statusPublished - 1 Jan 2016

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