Effect of inclusion or exclusion of epithelial cells in equine respiratory cytology analysis

K. J. Allen*, K. V. Tennant, S. H. Franklin

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Abstract

Published studies vary as to whether epithelial cells are included in differential counts for tracheal wash (TW) and bronchoalveolar lavage (BAL) cytology in horses. The aim of this study was to determine whether inclusion or exclusion of epithelial cells affects interpretation of airway cytology. Using criteria of >20% TW neutrophils, >10% BAL neutrophils and/or >5% BAL mast cells to indicate airway inflammation, there was a change in categorisation from ‘normal’ to ‘abnormal’ in 21%, 4% and 8% horses, respectively, when epithelial cells were excluded from differential counts. It is recommended that future equine respiratory research studies explicitly state whether epithelial cells are included or excluded in differential counts. A consensus on epithelial cell inclusion during cytology reporting is required.

Original languageEnglish
Article number105405
Number of pages2
JournalVeterinary Journal
Volume254
Early online date10 Nov 2019
DOIs
Publication statusPublished - 1 Dec 2019

Keywords

  • Bronchoalveolar lavage
  • Cytology
  • Epithelial cell
  • Horse
  • Tracheal wash

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