Effect of transcranial direct current stimulation on vestibular-ocular and vestibulo-perceptual thresholds

Artemis Kyriakareli, Sian Cousins, Vito E Pettorossi, Adolfo M Bronstein

Research output: Contribution to journalArticle (Academic Journal)peer-review

21 Citations (Scopus)

Abstract

Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased during as well as after tDCS stimulation. Body rotation was labeled as ipsilateral or contralateral to the anode side, but no difference was observed depending on the direction of rotation or hemisphere polarity. Threshold increase during tDCS was greater for VOR than for motion perception. 'Sham' stimulation had no effect on thresholds. We conclude that tDCS produces an immediate and sustained depression of cortical regions controlling VOR and movement perception. Temporoparietal areas appear to be involved in vestibular threshold modulation but the differential effects observed between VOR and perception suggest a partial dissociation between cortical processing of reflexive and perceptual responses.

Original languageEnglish
Pages (from-to)808-12
Number of pages5
JournalNeuroReport
Volume24
Issue number14
DOIs
Publication statusPublished - 2 Oct 2013

Structured keywords

  • Centre for Surgical Research

Keywords

  • Adult
  • Brain
  • Electrodes
  • Eye Movements
  • Female
  • Humans
  • Male
  • Middle Aged
  • Motion Perception
  • Reflex, Vestibulo-Ocular
  • Rotation
  • Vestibule, Labyrinth
  • Young Adult
  • Journal Article
  • Research Support, Non-U.S. Gov't

Fingerprint Dive into the research topics of 'Effect of transcranial direct current stimulation on vestibular-ocular and vestibulo-perceptual thresholds'. Together they form a unique fingerprint.

Cite this