Effects of magnetic stray fields from a 7 Tesla MRI scanner on neurocognition: a double-blind randomised crossover study

Lotte E. van Nierop; Pauline Slottje; Martine J. E. van Zandvoort; Frank de Vocht; Hans Kromhout

doi:10.1136/oemed-2011-100468

Effects of magnetic stray fields from a 7 Tesla MRI scanner on neurocognition: a double-blind randomised crossover study

Lotte E. van Nierop, Pauline Slottje, Martine J. E. van Zandvoort, Frank de Vocht, Hans Kromhout^*

^*Corresponding author for this work

Bristol Medical School (PHS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

55 Citations (Scopus)

Abstract

Objective This study characterises neurocognitive domains that are affected by movement-induced time-varying magnetic fields (TVMF) within a static magnetic stray field (SMF) of a 7 Tesla (T) MRI scanner.

Methods Using a double-blind randomised crossover design, 31 healthy volunteers were tested in a sham (0 T), low (0.5 T) and high (1.0 T) SMF exposure condition. Standardised head movements were made before every neurocognitive task to induce TVMF.

Results Of the six tested neurocognitive domains, we demonstrated that attention and concentration were negatively affected when exposed to TVMF within an SMF (varying from 5.0% to 21.1% per Tesla exposure, p

Conclusion Neurocognitive functioning is modulated when exposed to movement-induced TVMF within an SMF of a 7 T MRI scanner. Domains that were affected include attention/concentration and visuospatial orientation. Further studies are needed to better understand the mechanisms and possible practical safety and health implications of these acute neurocognitive effects.

Original language	English
Pages (from-to)	759-766
Number of pages	8
Journal	Occupational and Environmental Medicine
Volume	69
Issue number	10
DOIs	https://doi.org/10.1136/oemed-2011-100468
Publication status	Published - Oct 2012

Keywords

HEALTH COMPLAINTS
EXPOSURE
PERFORMANCE

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@article{63f6928e72d742daaf995fbfe9287e76,

title = "Effects of magnetic stray fields from a 7 Tesla MRI scanner on neurocognition: a double-blind randomised crossover study",

abstract = "Objective This study characterises neurocognitive domains that are affected by movement-induced time-varying magnetic fields (TVMF) within a static magnetic stray field (SMF) of a 7 Tesla (T) MRI scanner.Methods Using a double-blind randomised crossover design, 31 healthy volunteers were tested in a sham (0 T), low (0.5 T) and high (1.0 T) SMF exposure condition. Standardised head movements were made before every neurocognitive task to induce TVMF.Results Of the six tested neurocognitive domains, we demonstrated that attention and concentration were negatively affected when exposed to TVMF within an SMF (varying from 5.0% to 21.1% per Tesla exposure, pConclusion Neurocognitive functioning is modulated when exposed to movement-induced TVMF within an SMF of a 7 T MRI scanner. Domains that were affected include attention/concentration and visuospatial orientation. Further studies are needed to better understand the mechanisms and possible practical safety and health implications of these acute neurocognitive effects.",

keywords = "HEALTH COMPLAINTS, EXPOSURE, PERFORMANCE",

author = "{van Nierop}, {Lotte E.} and Pauline Slottje and {van Zandvoort}, {Martine J. E.} and {de Vocht}, Frank and Hans Kromhout",

year = "2012",

month = oct,

doi = "10.1136/oemed-2011-100468",

language = "English",

volume = "69",

pages = "759--766",

journal = "Occupational and Environmental Medicine",

issn = "1351-0711",

publisher = "BMJ Publishing Group",

number = "10",

}

TY - JOUR

T1 - Effects of magnetic stray fields from a 7 Tesla MRI scanner on neurocognition

T2 - a double-blind randomised crossover study

AU - van Nierop, Lotte E.

AU - Slottje, Pauline

AU - van Zandvoort, Martine J. E.

AU - de Vocht, Frank

AU - Kromhout, Hans

PY - 2012/10

Y1 - 2012/10

N2 - Objective This study characterises neurocognitive domains that are affected by movement-induced time-varying magnetic fields (TVMF) within a static magnetic stray field (SMF) of a 7 Tesla (T) MRI scanner.Methods Using a double-blind randomised crossover design, 31 healthy volunteers were tested in a sham (0 T), low (0.5 T) and high (1.0 T) SMF exposure condition. Standardised head movements were made before every neurocognitive task to induce TVMF.Results Of the six tested neurocognitive domains, we demonstrated that attention and concentration were negatively affected when exposed to TVMF within an SMF (varying from 5.0% to 21.1% per Tesla exposure, pConclusion Neurocognitive functioning is modulated when exposed to movement-induced TVMF within an SMF of a 7 T MRI scanner. Domains that were affected include attention/concentration and visuospatial orientation. Further studies are needed to better understand the mechanisms and possible practical safety and health implications of these acute neurocognitive effects.

AB - Objective This study characterises neurocognitive domains that are affected by movement-induced time-varying magnetic fields (TVMF) within a static magnetic stray field (SMF) of a 7 Tesla (T) MRI scanner.Methods Using a double-blind randomised crossover design, 31 healthy volunteers were tested in a sham (0 T), low (0.5 T) and high (1.0 T) SMF exposure condition. Standardised head movements were made before every neurocognitive task to induce TVMF.Results Of the six tested neurocognitive domains, we demonstrated that attention and concentration were negatively affected when exposed to TVMF within an SMF (varying from 5.0% to 21.1% per Tesla exposure, pConclusion Neurocognitive functioning is modulated when exposed to movement-induced TVMF within an SMF of a 7 T MRI scanner. Domains that were affected include attention/concentration and visuospatial orientation. Further studies are needed to better understand the mechanisms and possible practical safety and health implications of these acute neurocognitive effects.

KW - HEALTH COMPLAINTS

KW - EXPOSURE

KW - PERFORMANCE

U2 - 10.1136/oemed-2011-100468

DO - 10.1136/oemed-2011-100468

M3 - Article (Academic Journal)

C2 - 22930737

SN - 1351-0711

VL - 69

SP - 759

EP - 766

JO - Occupational and Environmental Medicine

JF - Occupational and Environmental Medicine

IS - 10

ER -

Effects of magnetic stray fields from a 7 Tesla MRI scanner on neurocognition: a double-blind randomised crossover study

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