Elucidating the genetics of craniofacial shape

David M. Evans

doi:10.1038/s41588-018-0065-4

Elucidating the genetics of craniofacial shape

David M. Evans^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate (Academic Journal)

3 Citations (Scopus)

Abstract

Alterations in craniofacial size and shape are apparent in many monogenic diseases and syndromes, but remarkably little is known about the genetics of face shape within healthy populations. This may be set to change following publication of a study that combines unsupervised hierarchical spectral clustering and canonical correlation analysis to help identify common genetic variants associated with craniofacial shape.

Original language	English
Number of pages	2
Journal	Nature Genetics
DOIs	https://doi.org/10.1038/s41588-018-0065-4
Publication status	E-pub ahead of print - 6 Mar 2018

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abstract = "Alterations in craniofacial size and shape are apparent in many monogenic diseases and syndromes, but remarkably little is known about the genetics of face shape within healthy populations. This may be set to change following publication of a study that combines unsupervised hierarchical spectral clustering and canonical correlation analysis to help identify common genetic variants associated with craniofacial shape.",

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AB - Alterations in craniofacial size and shape are apparent in many monogenic diseases and syndromes, but remarkably little is known about the genetics of face shape within healthy populations. This may be set to change following publication of a study that combines unsupervised hierarchical spectral clustering and canonical correlation analysis to help identify common genetic variants associated with craniofacial shape.

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