Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials

Mical Paul, Dafna Yahav, Abigail Fraser, Leonard Leibovici

Research output: Contribution to journalArticle (Academic Journal)peer-review

144 Citations (Scopus)

Abstract

Early, empirical broad-spectrum antibiotic treatment is the established practice for febrile neutropenia. Several beta-lactams are accepted for monotherapy. We asked whether patients' outcomes are influenced by the chosen beta-lactam.
Original languageEnglish
Pages (from-to)176-89
Number of pages14
JournalJournal of Antimicrobial Chemotherapy
Volume57
Issue number2
DOIs
Publication statusPublished - Feb 2006

Keywords

  • Anti-Bacterial Agents
  • Carbapenems
  • Cephalosporins
  • Enzyme Inhibitors
  • Fever
  • Humans
  • Neutropenia
  • Penicillanic Acid
  • Penicillins
  • Quality Assurance, Health Care
  • Randomized Controlled Trials as Topic
  • Treatment Outcome
  • beta-Lactamases

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