Enantioselective alpha-arylation of cyclohexanones with diaryl iodonium salts: Application to the synthesis of (-)-epibatidine

VK Aggarwal; B Olofsson

doi:10.1002/anie.200501745

Enantioselective alpha-arylation of cyclohexanones with diaryl iodonium salts: Application to the synthesis of (-)-epibatidine

VK Aggarwal^*, B Olofsson

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

117 Citations (Scopus)

Original language	English
Pages (from-to)	5516-5519
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	44
Issue number	34
DOIs	https://doi.org/10.1002/anie.200501745
Publication status	Published - 2005

Keywords

cyclohexanone
desymmetrization
enolates
epibatidine
iodonium salts
LITHIUM AMIDE BASES
SILYL ENOL ETHERS
ASYMMETRIC-SYNTHESIS
DIARYLIODONIUM SALTS
REGIOCONTROLLED SYNTHESIS
KETONES
CATALYSTS
FLUORIDE

Access to Document

10.1002/anie.200501745

Cite this

@article{93d1b22390114f8d98cc7cc69705ab37,

title = "Enantioselective alpha-arylation of cyclohexanones with diaryl iodonium salts: Application to the synthesis of (-)-epibatidine",

keywords = "cyclohexanone, desymmetrization, enolates, epibatidine, iodonium salts, LITHIUM AMIDE BASES, SILYL ENOL ETHERS, ASYMMETRIC-SYNTHESIS, DIARYLIODONIUM SALTS, REGIOCONTROLLED SYNTHESIS, KETONES, CATALYSTS, FLUORIDE",

author = "VK Aggarwal and B Olofsson",

year = "2005",

doi = "10.1002/anie.200501745",

language = "English",

volume = "44",

pages = "5516--5519",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "Wiley-VCH Verlag",

number = "34",

}

TY - JOUR

T1 - Enantioselective alpha-arylation of cyclohexanones with diaryl iodonium salts

T2 - Application to the synthesis of (-)-epibatidine

AU - Aggarwal, VK

AU - Olofsson, B

PY - 2005

Y1 - 2005

KW - cyclohexanone

KW - desymmetrization

KW - enolates

KW - epibatidine

KW - iodonium salts

KW - LITHIUM AMIDE BASES

KW - SILYL ENOL ETHERS

KW - ASYMMETRIC-SYNTHESIS

KW - DIARYLIODONIUM SALTS

KW - REGIOCONTROLLED SYNTHESIS

KW - KETONES

KW - CATALYSTS

KW - FLUORIDE

U2 - 10.1002/anie.200501745

DO - 10.1002/anie.200501745

M3 - Article (Academic Journal)

VL - 44

SP - 5516

EP - 5519

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 34

ER -