Enantioselective alpha-arylation of cyclohexanones with diaryl iodonium salts: Application to the synthesis of (-)-epibatidine

VK Aggarwal*, B Olofsson

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

117 Citations (Scopus)
Original languageEnglish
Pages (from-to)5516-5519
Number of pages4
JournalAngewandte Chemie - International Edition
Volume44
Issue number34
DOIs
Publication statusPublished - 2005

Keywords

  • cyclohexanone
  • desymmetrization
  • enolates
  • epibatidine
  • iodonium salts
  • LITHIUM AMIDE BASES
  • SILYL ENOL ETHERS
  • ASYMMETRIC-SYNTHESIS
  • DIARYLIODONIUM SALTS
  • REGIOCONTROLLED SYNTHESIS
  • KETONES
  • CATALYSTS
  • FLUORIDE

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