Abstract
Pd(0)-systems modified with SPINOL-derived phosphoramidate ligands promote highly enantioselective aza-Heck cyclizations of alkenyl N-(tosyloxy)carbamates. The method provides versatile access to challenging N-heterocycles and represents
the broadest scope enantioselective aza-Heck protocol developed so far.
the broadest scope enantioselective aza-Heck protocol developed so far.
Original language | English |
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Pages (from-to) | 3356-3360 |
Number of pages | 5 |
Journal | Journal of the American Chemical Society |
Volume | 141 |
Issue number | 8 |
Early online date | 9 Feb 2019 |
DOIs | |
Publication status | Published - 18 Feb 2019 |