Endogenous TWIST expression and differentiation are opposite during human muscle development

A Koutsoulidou, NP Mastroyiannopoulos, D Furling, JB Uney, L Phylactou

Research output: Contribution to journalArticle (Academic Journal)peer-review

4 Citations (Scopus)

Abstract

TWIST is a transcription factor expressed during early embryonic development. In this study we investigate the expression of TWIST during human muscle development. Human TWIST was found to be endogenously expressed in human fetal myoblasts, and its expression decreased during late stages of development. Myoblasts showed an increasing capacity to differentiate in vitro during development. This inversely proportional relation between TWIST and differentiation capacity of myoblasts suggests that TWIST is involved in the regulation of muscle development. Muscle Nerve, 2011.
Translated title of the contributionEndogenous TWIST expression and differentiation are opposite during human muscle development
Original languageEnglish
Pages (from-to)984 - 986
Number of pages3
JournalMuscle and Nerve
Volume44(6)
Publication statusPublished - Dec 2011

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