Enhanced PIP3 signaling in POMC neurons causes K-ATP channel activation and leads to diet-sensitive obesity

L Plum; XS Ma; B Hampel; N Balthasar; R Coppari; H Munzberg; M Shanaborough; D Burdakov; E Rother; R Janoschek; J Alber; BF Belgardt; L Koch; F Schwenk; C Fekete; A Suzuki; TW Mak; W Krone; TL Horvath; FM Ashcroft; JC Bruning

doi:10.1172/JCI27123

Enhanced PIP3 signaling in POMC neurons causes K-ATP channel activation and leads to diet-sensitive obesity

L Plum
, XS Ma
, B Hampel
, N Balthasar
, R Coppari
, H Munzberg
, M Shanaborough
, D Burdakov
, E Rother
, R Janoschek
, J Alber
, BF Belgardt
, L Koch
, F Schwenk
, C Fekete
, A Suzuki
, TW Mak
, W Krone
, TL Horvath
, FM Ashcroft

JC Bruning

Research output: Contribution to journal › Article (Academic Journal) › peer-review

304 Citations (Scopus)

Translated title of the contribution	Enhanced PIP3 signaling in POMC neurons causes K-ATP channel activation and leads to diet-sensitive obesity
Original language	English
Pages (from-to)	1886 - 1901
Number of pages	15
Journal	Journal of Clinical Investigation
Volume	116
DOIs	https://doi.org/10.1172/JCI27123
Publication status	Published - Jul 2006

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SDG 3 Good Health and Well-being

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10.1172/JCI27123

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Cite this

Plum, L., Ma, XS., Hampel, B., Balthasar, N., Coppari, R., Munzberg, H., Shanaborough, M., Burdakov, D., Rother, E., Janoschek, R., Alber, J., Belgardt, BF., Koch, L., Schwenk, F., Fekete, C., Suzuki, A., Mak, TW., Krone, W., Horvath, TL., ... Bruning, JC. (2006). Enhanced PIP3 signaling in POMC neurons causes K-ATP channel activation and leads to diet-sensitive obesity. Journal of Clinical Investigation, 116, 1886 - 1901. https://doi.org/10.1172/JCI27123

@article{dccc89f5ed594ff3bcdc720a8d2be2ee,

title = "Enhanced PIP3 signaling in POMC neurons causes K-ATP channel activation and leads to diet-sensitive obesity",

author = "L Plum and XS Ma and B Hampel and N Balthasar and R Coppari and H Munzberg and M Shanaborough and D Burdakov and E Rother and R Janoschek and J Alber and BF Belgardt and L Koch and F Schwenk and C Fekete and A Suzuki and TW Mak and W Krone and TL Horvath and FM Ashcroft and JC Bruning",

year = "2006",

month = jul,

doi = "10.1172/JCI27123",

language = "English",

volume = "116",

pages = "1886 -- 1901",

journal = "Journal of Clinical Investigation",

issn = "1558-8238",

publisher = "American Society for Clinical Investigation",

}

Plum, L, Ma, XS, Hampel, B, Balthasar, N, Coppari, R, Munzberg, H, Shanaborough, M, Burdakov, D, Rother, E, Janoschek, R, Alber, J, Belgardt, BF, Koch, L, Schwenk, F, Fekete, C, Suzuki, A, Mak, TW, Krone, W, Horvath, TL, Ashcroft, FM & Bruning, JC 2006, 'Enhanced PIP3 signaling in POMC neurons causes K-ATP channel activation and leads to diet-sensitive obesity', Journal of Clinical Investigation, vol. 116, pp. 1886 - 1901. https://doi.org/10.1172/JCI27123

TY - JOUR

T1 - Enhanced PIP3 signaling in POMC neurons causes K-ATP channel activation and leads to diet-sensitive obesity

AU - Plum, L

AU - Ma, XS

AU - Hampel, B

AU - Balthasar, N

AU - Coppari, R

AU - Munzberg, H

AU - Shanaborough, M

AU - Burdakov, D

AU - Rother, E

AU - Janoschek, R

AU - Alber, J

AU - Belgardt, BF

AU - Koch, L

AU - Schwenk, F

AU - Fekete, C

AU - Suzuki, A

AU - Mak, TW

AU - Krone, W

AU - Horvath, TL

AU - Ashcroft, FM

AU - Bruning, JC

PY - 2006/7

Y1 - 2006/7

U2 - 10.1172/JCI27123

DO - 10.1172/JCI27123

M3 - Article (Academic Journal)

SN - 1558-8238

VL - 116

SP - 1886

EP - 1901

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

ER -