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Abstract
Genome-wide association studies have eclipsed candidate gene association studies in genetic epidemiology in providing robust, unbiased evidence for the role of genetic variants in complex traits and diseases. The hypothesis-free nature of GWAS inherently minimises the risk of publication bias, and where available these studies should be considered in any meta-analysis of genetic association studies.
Original language | English |
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Pages (from-to) | 257-258 |
Number of pages | 2 |
Journal | Gene |
Volume | 556 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1 Jan 2015 |
Keywords
- ENOS
- Funnel plot
- Genetic association
- GWAS
- Meta-analysis
- Systematic review
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Dive into the research topics of 'ENOS and coronary artery disease: Publication bias and the eclipse of hypothesis-driven meta-analysis in genetic association studies'. Together they form a unique fingerprint.Projects
- 2 Finished