Epigenetic clocks for gestational age: statistical and study design considerations

Andrew Simpkin, Matthew Suderman, Laura Howe

Research output: Contribution to journalArticle (Academic Journal)peer-review

12 Citations (Scopus)
220 Downloads (Pure)

Abstract

In this letter to the editor, we highlight some concerns with a recently published method to estimate gestational age at delivery from DNA methylation data. We conduct novel analyses to highlight the implications of different choices in study design and statistical methods for the prediction of phenotypes from methylation data.
Original languageEnglish
Article number100
Number of pages2
JournalClinical Epigenetics
Volume9
DOIs
Publication statusPublished - 15 Sep 2017

Keywords

  • Prediction
  • DNA methylation
  • Gestational age
  • Epigenetic clock

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