ESCAPE: a randomised controlled trial of computer-tailored smoking cessation advice in primary care

Hazel M Gilbert, Baptiste Leurent, Stephen Sutton, Camille Alexis-Garsee, Richard W Morris, Irwin Nazareth

Research output: Contribution to journalArticle (Academic Journal)peer-review

14 Citations (Scopus)


AIMS: To evaluate the effectiveness of tailored cessation advice reports, including levels of reading ability, compared with a generic self-help booklet.

DESIGN: Participants were randomised to receive standard non-tailored information or to receive standard information plus a cessation advice report and a progress report, both tailored to individual characteristics.

SETTING: One hundred and twenty-three general practices located throughout the UK.

PARTICIPANTS: Questionnaires were mailed to 58 660 current cigarette smokers aged 18-65 years, identified from general practitioner records. Of the 6911 (11.8%) who completed the questionnaire, provided consent and were enrolled into the study, 6697 (11.4%) were included in the analysis.

MEASUREMENTS: Follow-up was by postal questionnaire sent six months after randomisation, or by telephone interview for participants failing to return the questionnaire. The primary outcome was self-reported prolonged abstinence for at least three months at the six-month follow-up.

FINDINGS: Quit rates on the primary outcome were not significantly different (3.2% versus 2.7%) (OR = 1.20, 95% CI [0.94, 1.54], P = 0.15). A significantly higher proportion of intervention group participants made a quit attempt during the follow-up period (32.3% versus 29.6%; OR = 1.13, 95% CI [1.01, 1.26], P = 0.026).

CONCLUSION: ESCAPE, a brief tailored smoking cessation intervention delivered by post and designed to reach a wide population of smokers, appears to increase the rate at which smokers try to stop, but if there is an effect on prolonged abstinence it is small.

Original languageEnglish
Pages (from-to)811-9
Number of pages9
Issue number4
Publication statusPublished - Apr 2013

Bibliographical note

© 2012 The Authors, Addiction © 2012 Society for the Study of Addiction.


  • Adolescent
  • Adult
  • Aged
  • Counseling
  • Female
  • General Practice
  • Humans
  • Male
  • Middle Aged
  • Patient Education as Topic
  • Questionnaires
  • Self Care
  • Smoking Cessation
  • Therapy, Computer-Assisted
  • Treatment Outcome
  • Young Adult


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