Establishing non-inferiority in treatment trials in psychiatry - guidelines from an Expert Consensus Meeting

David J Nutt; C. Allgulander; Y. Lecrubier; Tim Peters; U. Wittchen

doi:10.1177/0269881108091068

Establishing non-inferiority in treatment trials in psychiatry - guidelines from an Expert Consensus Meeting

David J Nutt^*
, C. Allgulander
, Y. Lecrubier
, Tim Peters
, U. Wittchen

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

25 Citations (Scopus)

Abstract

Comparing the efficacy of different treatments in psychiatry is difficult for many reasons, even when they are investigated in 'head-to-head' studies. A consensus meeting was, therefore, held to produce best practice guidelines for such studies. This article presents the conclusions of this consensus and illustrates it using published data in the field of antidepressant treatment of generalized anxiety disorder.

Original language	English
Pages (from-to)	409-416
Number of pages	8
Journal	Journal of Psychopharmacology
Volume	22
Issue number	4
DOIs	https://doi.org/10.1177/0269881108091068
Publication status	Published - Jun 2008

Keywords

Clinical trials
Duloxetine
GAD
Non-inferiority
Venlafaxine

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abstract = "Comparing the efficacy of different treatments in psychiatry is difficult for many reasons, even when they are investigated in 'head-to-head' studies. A consensus meeting was, therefore, held to produce best practice guidelines for such studies. This article presents the conclusions of this consensus and illustrates it using published data in the field of antidepressant treatment of generalized anxiety disorder. ",

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AU - Peters, Tim

AU - Wittchen, U.

PY - 2008/6

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KW - Clinical trials

KW - Duloxetine

KW - GAD

KW - Non-inferiority

KW - Venlafaxine

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Establishing non-inferiority in treatment trials in psychiatry - guidelines from an Expert Consensus Meeting

Abstract

Keywords

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