Evaluating and contextualizing volatile organic compounds in dog training breath samples from a patient with type 1 diabetes

Zoe Parr-Cortes, Nicola J Rooney*, Madeleine Wheatstone, Toby Stock, Claire Pesterfield, Claire Guest, Carsten Muller

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

1 Citation (Scopus)
3 Downloads (Pure)

Abstract

Tight control of blood glucose can reduce the risk of severe health consequences of type 1 diabetes. For individuals with impaired awareness of hypoglycemia, glycemic control can be especially challenging. Fear of hypoglycemic events can lead individuals to adjust their glucose management resulting in poor glycemic control. Glycemic alert dogs trained on breath odor have been shown to accurately alert to changes in blood glucose in individuals with type 1 diabetes, providing them with an opportunity to intervene before dangerous fluctuations occur. By analyzing the volatile organic compounds (VOCs) of breath samples used during glycemic alert dog training, the aim of this study is to see if we, too, can detect differences in odor associated with blood glucose in type 1 diabetes. Breath samples from an individual with type 1 diabetes were collected during euglycemia, hypoglycemia, and hyperglycemia and analyzed using thermal desorption gas-chromatography time-of-flight mass-spectrometry. Statistical analysis w
Original languageEnglish
Pages (from-to)62-75
Number of pages14
JournalJournal of Veterinary Behavior: Clinical Applications and Research
Volume75
Early online date14 Aug 2024
DOIs
Publication statusPublished - 1 Sept 2024

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