Evaluation of 'care bundles' for patients with chronic obstructive pulmonary disease (COPD): a multisite study in the UK

Katherine Morton, Stephanie MacNeill, Emily Sanderson, Padraig Dixon, Anna King, Sue Jenkins, Chris Metcalfe, Alison R G Shaw, Melanie Chalder, Jonathan Benger, William Hollingworth, James Calvert, Sarah Purdy

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Background Chronic obstructive pulmonary disease (COPD) accounts for 10% of emergency hospital admissions in the United Kingdom annually. Nearly 33% of patients are re-admitted within 28 days of discharge. We evaluated the effectiveness of implementing standardised packages of care called ‘care bundles’ on COPD re-admission, emergency department (ED) attendance, mortality, costs and process of care.
Methods Mixed-methods controlled before-and-after study with nested case studies. 31 acute hospitals in England and Wales which introduced COPD care bundles (implementation sites) or provided usual care (comparator sites) were recruited and provided monthly aggregate data. 14 sites provided additional individual patient data. Participants were adults admitted with an acute exacerbation of COPD.
Results There was no evidence that care bundles reduced 28-day COPD re-admission rates: OR=1·02 (95% CI:0·83, 1·26). However, the rate of ED attendance was reduced in implementation sites over and above that in comparator sites (implementation: IRR=0·63 (95% CI:0·56,0·71); comparator: IRR=1·12 (95% CI:1·02,1·24); group-time interaction p<0·001). At implementation sites, delivery of all bundle elements was higher but was only achieved in 2.2% (admissions bundle) and 7.6% (discharge bundle) of cases. There was no evidence of cost effectiveness. Staff viewed bundles positively, believing they help standardise practice and facilitate communication between clinicians. However, they lacked skills in change management leading to inconsistent implementation.

Discussion COPD care bundles were not effectively implemented in this study. They were associated with a reduced number of subsequent ED attendances, but not with change in re-admissions, mortality or reduced costs. This is unsurprising given the low level of bundle uptake in implementation sites and it remains to be determined if COPD care bundles affect patient care and outcomes when they are effectively implemented.
Original languageEnglish
Article numbere000425
Number of pages10
JournalBMJ Open Respiratory Research
Issue number1
Publication statusPublished - 30 May 2019

Structured keywords

  • BTC (Bristol Trials Centre)
  • BRTC
  • Centre for Surgical Research


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