Evaluation of the repeatability of ultrasound scanning for detection of feline polycystic kidney disease

Sheila J Wills; EL Barrett; FJ Barr; KJ Bradley; CR Helps; MJ Cannon; TJ Gruffydd-Jones

doi:10.1016/j.jfms.2009.07.002

Evaluation of the repeatability of ultrasound scanning for detection of feline polycystic kidney disease

Sheila J Wills, EL Barrett, FJ Barr, KJ Bradley, CR Helps, MJ Cannon, TJ Gruffydd-Jones

Research output: Contribution to journal › Article (Academic Journal) › peer-review

19 Citations (Scopus)

Abstract

Polycystic kidney disease (PKD) is the most prevalent inherited genetic disease in cats with Persian and Persian-related breeds predominantly affected. Diagnosis of PKD relied on ultrasound scanning until the recent development of the PKD gene test. However, gene testing has limitations as it will only identify the autosomal dominant form of PKD and not other forms of cystic kidney disease. Ultrasound scanning also has the advantage of being able to assess the severity and progression of disease in PKD affected cats. The aim of this study was to demonstrate the repeatability of ultrasound scanning in the detection of PKD and to assess progression of the disease over time. This study demonstrated 100% repeatability of ultrasound scanning in the detection of PKD and has also demonstrated progression of disease in 75% of PKD positive cats assessed over a 1-year period.

Translated title of the contribution	Evaluation of the repeatability of ultrasound scanning for detection of feline polycystic kidney disease
Original language	English
Pages (from-to)	993 - 996
Number of pages	4
Journal	Feline Focus
Volume	11
Issue number	12
DOIs	https://doi.org/10.1016/j.jfms.2009.07.002
Publication status	Published - Dec 2009

Bibliographical note

Other: Available online 5 August 2009

Access to Document

10.1016/j.jfms.2009.07.002

Handle.net

Persistent link

Cite this

@article{b8a79283fcdf49b2a68e3bd7b1d04400,

title = "Evaluation of the repeatability of ultrasound scanning for detection of feline polycystic kidney disease",

abstract = " Polycystic kidney disease (PKD) is the most prevalent inherited genetic disease in cats with Persian and Persian-related breeds predominantly affected. Diagnosis of PKD relied on ultrasound scanning until the recent development of the PKD gene test. However, gene testing has limitations as it will only identify the autosomal dominant form of PKD and not other forms of cystic kidney disease. Ultrasound scanning also has the advantage of being able to assess the severity and progression of disease in PKD affected cats. The aim of this study was to demonstrate the repeatability of ultrasound scanning in the detection of PKD and to assess progression of the disease over time. This study demonstrated 100% repeatability of ultrasound scanning in the detection of PKD and has also demonstrated progression of disease in 75% of PKD positive cats assessed over a 1-year period.",

author = "Wills, {Sheila J} and EL Barrett and FJ Barr and KJ Bradley and CR Helps and MJ Cannon and TJ Gruffydd-Jones",

note = "Other: Available online 5 August 2009",

year = "2009",

month = dec,

doi = "10.1016/j.jfms.2009.07.002",

language = "English",

volume = "11",

pages = "993 -- 996",

journal = "Feline Focus",

issn = "2057-3472",

publisher = "International Society of Feline Medicine (ISFM)",

number = "12",

}

TY - JOUR

T1 - Evaluation of the repeatability of ultrasound scanning for detection of feline polycystic kidney disease

AU - Wills, Sheila J

AU - Barrett, EL

AU - Barr, FJ

AU - Bradley, KJ

AU - Helps, CR

AU - Cannon, MJ

AU - Gruffydd-Jones, TJ

N1 - Other: Available online 5 August 2009

PY - 2009/12

Y1 - 2009/12

N2 - Polycystic kidney disease (PKD) is the most prevalent inherited genetic disease in cats with Persian and Persian-related breeds predominantly affected. Diagnosis of PKD relied on ultrasound scanning until the recent development of the PKD gene test. However, gene testing has limitations as it will only identify the autosomal dominant form of PKD and not other forms of cystic kidney disease. Ultrasound scanning also has the advantage of being able to assess the severity and progression of disease in PKD affected cats. The aim of this study was to demonstrate the repeatability of ultrasound scanning in the detection of PKD and to assess progression of the disease over time. This study demonstrated 100% repeatability of ultrasound scanning in the detection of PKD and has also demonstrated progression of disease in 75% of PKD positive cats assessed over a 1-year period.

AB - Polycystic kidney disease (PKD) is the most prevalent inherited genetic disease in cats with Persian and Persian-related breeds predominantly affected. Diagnosis of PKD relied on ultrasound scanning until the recent development of the PKD gene test. However, gene testing has limitations as it will only identify the autosomal dominant form of PKD and not other forms of cystic kidney disease. Ultrasound scanning also has the advantage of being able to assess the severity and progression of disease in PKD affected cats. The aim of this study was to demonstrate the repeatability of ultrasound scanning in the detection of PKD and to assess progression of the disease over time. This study demonstrated 100% repeatability of ultrasound scanning in the detection of PKD and has also demonstrated progression of disease in 75% of PKD positive cats assessed over a 1-year period.

U2 - 10.1016/j.jfms.2009.07.002

DO - 10.1016/j.jfms.2009.07.002

M3 - Article (Academic Journal)

C2 - 19660972

SN - 2057-3472

VL - 11

SP - 993

EP - 996

JO - Feline Focus

JF - Feline Focus

IS - 12

ER -

Evaluation of the repeatability of ultrasound scanning for detection of feline polycystic kidney disease

Abstract

Bibliographical note

Access to Document

Handle.net

Fingerprint

Cite this