Evolution of Plant Pathogenesis in Pseudomonas syringae: A Genomics Perspective

Heath E. O'Brien*, Shalabh Thakur, David S. Guttman

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

63 Citations (Scopus)

Abstract

The phytopathogenic bacterium Pseudomonas syringae causes serious diseases in a wide range of important crop plants, with recent severe outbreaks on the New Zealand kiwifruit crop and among British horse chestnut trees. Next-generation genome sequencing of over 25 new strains has greatly broadened our understanding of how this species adapts to a diverse range of plant hosts. Not unexpectedly, the genomes were found to be highly dynamic, and extensive polymorphism was found in the distribution of type III secreted effectors (T3SEs) and other virulence-associated genes, even among strains within the same pathovar. An underexplored area brought to light by these data is the specific metabolic adaptations required for growth on woody hosts. These studies provide a tremendous wealth of candidates for more refined functional characterization, which is greatly enhancing our ability to disentangle the web of host-pathogen interactions that determine disease outcomes.

Original languageEnglish
Title of host publicationANNUAL REVIEW OF PHYTOPATHOLOGY, VOL 49
EditorsNK VanAlfen, G Bruening, JE Leach
Place of PublicationPALO ALTO
PublisherAnnual Reviews
Pages269-289
Number of pages21
ISBN (Print)978-0-8243-1349-4
DOIs
Publication statusPublished - 2011

Publication series

NameAnnual Review of Phytopathology
PublisherANNUAL REVIEWS
Volume49
ISSN (Print)0066-4286

Keywords

  • host specificity
  • plant pathology
  • type III effector
  • virulence factor
  • PV. TOMATO DC3000
  • III SECRETION SYSTEM
  • EXCHANGEABLE EFFECTOR LOCI
  • BIOSYNTHETIC GENE-CLUSTER
  • HRP PATHOGENICITY ISLAND
  • SHORT DNA-SEQUENCES
  • GENOMEWIDE IDENTIFICATION
  • NUCLEOTIDE-SEQUENCE
  • MAXIMUM-LIKELIHOOD
  • PHASEOLICOLA 1448A

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