Evolution of the protein repertoire

C Chothia, J Gough, C Vogel, SA Teichmann

Research output: Contribution to journalArticle (Academic Journal)

360 Citations (Scopus)


Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.
Translated title of the contributionEvolution of the protein repertoire
Original languageEnglish
Article number1701-1703
Pages (from-to)1701 - 1703
Number of pages3
Volume300 (5626)
Publication statusPublished - Jun 2003

Bibliographical note

Publisher: American Assoc. for the Advancement of Science

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    Chothia, C., Gough, J., Vogel, C., & Teichmann, SA. (2003). Evolution of the protein repertoire. Science, 300 (5626), 1701 - 1703. [1701-1703]. https://doi.org/10.1126/science.1085371