Evolution of the protein repertoire

C Chothia; J Gough; C Vogel; SA Teichmann

doi:10.1126/science.1085371

Evolution of the protein repertoire

C Chothia, J Gough, C Vogel, SA Teichmann

Research output: Contribution to journal › Article (Academic Journal) › peer-review

469 Citations (Scopus)

Abstract

Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.

Translated title of the contribution	Evolution of the protein repertoire
Original language	English
Article number	1701-1703
Pages (from-to)	1701 - 1703
Number of pages	3
Journal	Science
Volume	300 (5626)
DOIs	https://doi.org/10.1126/science.1085371
Publication status	Published - Jun 2003

Bibliographical note

Publisher: American Assoc. for the Advancement of Science

Access to Document

10.1126/science.1085371

Handle.net

Persistent link

Cite this

@article{ba97b473a85346f49db11c81410a5a96,

title = "Evolution of the protein repertoire",

abstract = "Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50\% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.",

author = "C Chothia and J Gough and C Vogel and SA Teichmann",

note = "Publisher: American Assoc. for the Advancement of Science",

year = "2003",

month = jun,

doi = "10.1126/science.1085371",

language = "English",

volume = "300 (5626)",

pages = "1701 -- 1703",

journal = "Science",

issn = "1095-9203",

publisher = "American Association for the Advancement of Science",

}

TY - JOUR

T1 - Evolution of the protein repertoire

AU - Chothia, C

AU - Gough, J

AU - Vogel, C

AU - Teichmann, SA

N1 - Publisher: American Assoc. for the Advancement of Science

PY - 2003/6

Y1 - 2003/6

N2 - Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.

AB - Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.

U2 - 10.1126/science.1085371

DO - 10.1126/science.1085371

M3 - Article (Academic Journal)

SN - 1095-9203

VL - 300 (5626)

SP - 1701

EP - 1703

JO - Science

JF - Science

M1 - 1701-1703

ER -

Evolution of the protein repertoire

Abstract

Bibliographical note

Access to Document

Handle.net

Fingerprint

Cite this