Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence

Lihini Gunawardana, Stanley Zammit, Glyn Lewis, David Gunnell, Chris Hollis, Dieter Wolke, Glynn Harrison

Research output: Contribution to journalArticle (Academic Journal)

15 Citations (Scopus)

Abstract

Children and adolescents who report psychotic symptoms in non-clinical samples are at an increased risk of developing schizophrenia. Study of such 'high risk' groups may increase our understanding of early risk factors for psychotic illnesses. Maternal infection during pregnancy is associated with an increased risk of schizophrenia in the offspring, and it has been hypothesised that exposure to maternal intake of analgesics during pregnancy, taken to alleviate the symptoms of viral infections, may partly explain this association. The aim of this study was to examine the relationship between maternal use of aspirin and other analgesics during pregnancy and the occurrence of psychotic symptoms in the offspring.
Original languageEnglish
Pages (from-to)220-5
Number of pages6
JournalSchizophrenia Research
Volume126
Issue number1-3
DOIs
Publication statusPublished - 2011

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