Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence

Lihini Gunawardana; Stanley Zammit; Glyn Lewis; David Gunnell; Chris Hollis; Dieter Wolke; Glynn Harrison

doi:10.1016/j.schres.2010.10.021

Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence

Lihini Gunawardana, Stanley Zammit, Glyn Lewis, David Gunnell, Chris Hollis, Dieter Wolke, Glynn Harrison

Research output: Contribution to journal › Article (Academic Journal)

15 Citations (Scopus)

Abstract

Children and adolescents who report psychotic symptoms in non-clinical samples are at an increased risk of developing schizophrenia. Study of such 'high risk' groups may increase our understanding of early risk factors for psychotic illnesses. Maternal infection during pregnancy is associated with an increased risk of schizophrenia in the offspring, and it has been hypothesised that exposure to maternal intake of analgesics during pregnancy, taken to alleviate the symptoms of viral infections, may partly explain this association. The aim of this study was to examine the relationship between maternal use of aspirin and other analgesics during pregnancy and the occurrence of psychotic symptoms in the offspring.

Original language	English
Pages (from-to)	220-5
Number of pages	6
Journal	Schizophrenia Research
Volume	126
Issue number	1-3
DOIs	https://doi.org/10.1016/j.schres.2010.10.021
Publication status	Published - 2011

Access to Document

10.1016/j.schres.2010.10.021

Fingerprint Dive into the research topics of 'Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence'. Together they form a unique fingerprint.

Projects

1 Finished

EXTENSION OF RD1321 VIA IOP.

Golding, J.

1/02/01 → 1/02/06

Project: Research

Cite this

Gunawardana, L., Zammit, S., Lewis, G., Gunnell, D., Hollis, C., Wolke, D., & Harrison, G. (2011). Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence. Schizophrenia Research, 126(1-3), 220-5. https://doi.org/10.1016/j.schres.2010.10.021

@article{3d16ddc476654a078e6f9feab2482847,

title = "Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence",

abstract = "Children and adolescents who report psychotic symptoms in non-clinical samples are at an increased risk of developing schizophrenia. Study of such 'high risk' groups may increase our understanding of early risk factors for psychotic illnesses. Maternal infection during pregnancy is associated with an increased risk of schizophrenia in the offspring, and it has been hypothesised that exposure to maternal intake of analgesics during pregnancy, taken to alleviate the symptoms of viral infections, may partly explain this association. The aim of this study was to examine the relationship between maternal use of aspirin and other analgesics during pregnancy and the occurrence of psychotic symptoms in the offspring.",

author = "Lihini Gunawardana and Stanley Zammit and Glyn Lewis and David Gunnell and Chris Hollis and Dieter Wolke and Glynn Harrison",

year = "2011",

doi = "10.1016/j.schres.2010.10.021",

language = "English",

volume = "126",

pages = "220--5",

journal = "Schizophrenia Research",

issn = "0920-9964",

publisher = "Elsevier",

number = "1-3",

}

Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence. / Gunawardana, Lihini; Zammit, Stanley; Lewis, Glyn; Gunnell, David; Hollis, Chris; Wolke, Dieter; Harrison, Glynn.

In: Schizophrenia Research, Vol. 126, No. 1-3, 2011, p. 220-5.

Research output: Contribution to journal › Article (Academic Journal)

TY - JOUR

T1 - Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence

AU - Gunawardana, Lihini

AU - Zammit, Stanley

AU - Lewis, Glyn

AU - Gunnell, David

AU - Hollis, Chris

AU - Wolke, Dieter

AU - Harrison, Glynn

PY - 2011

Y1 - 2011

N2 - Children and adolescents who report psychotic symptoms in non-clinical samples are at an increased risk of developing schizophrenia. Study of such 'high risk' groups may increase our understanding of early risk factors for psychotic illnesses. Maternal infection during pregnancy is associated with an increased risk of schizophrenia in the offspring, and it has been hypothesised that exposure to maternal intake of analgesics during pregnancy, taken to alleviate the symptoms of viral infections, may partly explain this association. The aim of this study was to examine the relationship between maternal use of aspirin and other analgesics during pregnancy and the occurrence of psychotic symptoms in the offspring.

AB - Children and adolescents who report psychotic symptoms in non-clinical samples are at an increased risk of developing schizophrenia. Study of such 'high risk' groups may increase our understanding of early risk factors for psychotic illnesses. Maternal infection during pregnancy is associated with an increased risk of schizophrenia in the offspring, and it has been hypothesised that exposure to maternal intake of analgesics during pregnancy, taken to alleviate the symptoms of viral infections, may partly explain this association. The aim of this study was to examine the relationship between maternal use of aspirin and other analgesics during pregnancy and the occurrence of psychotic symptoms in the offspring.

U2 - 10.1016/j.schres.2010.10.021

DO - 10.1016/j.schres.2010.10.021

M3 - Article (Academic Journal)

C2 - 21146371

VL - 126

SP - 220

EP - 225

JO - Schizophrenia Research

JF - Schizophrenia Research

SN - 0920-9964

IS - 1-3

ER -