Excessive appetitive arousal in Prader-Willi syndrome

E. C. Hinton*, A. R. Isles, N. M. Williams, J. A. Parkinson

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

12 Citations (Scopus)

Abstract

This study focused on genetic and behavioural aspects of one important component of the motivation to eat - how appetitive arousal is elicited through the presentation of food-associated Stimuli. Individuals with Prader-Willi syndrome, a genetic disorder associated with hyperphagia, and control participants completed a computerised response task in the presence of motivational stimuli. in controls, appetitive arousal was specific to particular Stimuli. In contrast, individuals with PWS showed a non-specific pattern of arousal. Over-activation of the anticipatory motivation system may be one consequence of the genetic disorder in PWS. (C) 2009 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)225-228
Number of pages4
JournalAppetite
Volume54
Issue number1
DOIs
Publication statusPublished - Feb 2010

Structured keywords

  • Brain and Behaviour

Keywords

  • Food
  • Motivational arousal
  • Prader-Willi syndrome
  • Genetics
  • Learning
  • Craving
  • PAVLOVIAN-INSTRUMENTAL TRANSFER
  • NEURAL BASIS
  • MOTIVATION
  • AMYGDALA
  • HUNGER
  • GENETICS
  • STIMULI
  • SATIETY
  • OBESITY
  • HUMANS

Cite this