Exploring fungal RiPPs from the perspective of chemical ecology

Rosie Ford, Gary D Foster, Andrew M. Bailey*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

1 Citation (Scopus)
35 Downloads (Pure)


Since the initial detection, in 2007, of fungal ribosomally synthesised and post-translationally modified peptides (RiPPs), this group of natural products has undergone rapid expansion, with four separate classes now recognised: amatoxins/phallotoxins, borosins, dikaritins, and epichloëcyclins. Largely due to their historically anthropocentric employment in medicine and agriculture, novel fungal proteins and peptides are seldom investigated in relation to the fungus itself. Therefore, although the benefits these compounds confer to humans are often realised, their evolutionary advantage to the fungus, the reason for their continued production, is often obscure or ignored. This review sets out to summarise current knowledge on how these small peptide-derived products influence their producing species and surrounding biotic environment.
Original languageEnglish
Article number12
Pages (from-to)1-12
Number of pages12
JournalFungal Biology and Biotechnology
Issue number1
Publication statusPublished - 25 Jun 2022

Bibliographical note

Funding Information:
Rosie Ford is funded by the Biotechnology and Biological Sciences Research Council under a South West Biosciences Doctoral Training Partnership studentship (BB/M009122/1).

Publisher Copyright:
© 2022, The Author(s).


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