Exploring the genetic aetiology of trust in adolescents: Combined twin and DNA analyses

Robyn E Wootton, Oliver S. Davis, Abigail L Mottershaw, Adele Wang, Claire M A Haworth

Research output: Contribution to journalArticle (Academic Journal)peer-review

3 Citations (Scopus)
244 Downloads (Pure)

Abstract

Behavioural traits generally show moderate to strong genetic influence, with heritability estimates of around 50%. Some recent research has suggested that trust may be an exception because it is more strongly influenced by social interactions. In a sample of over 7,000 adolescent twins from the UK’s Twins Early Development Study we found broad sense heritability estimates of 57% for generalised trust and 51% for trust in friends. GREML estimates in the same sample indicate that 21% of the narrow sense genetic variance can be explained by common single nucleotide polymorphisms for generalised trust and 43% for trust in friends. As expected, this implies a large amount of unexplained heritability, although power is low for estimating DNA-based heritability. The missing heritability may be accounted for by interactions between DNA and the social environment during development or via gene-environment correlations with rare variants. How these genes and environments correlate seem especially important for the development of trust.
Original languageEnglish
Pages (from-to)638-646
Number of pages9
JournalTwin Research and Human Genetics
Volume19
Issue number6
Early online date17 Nov 2016
DOIs
Publication statusPublished - Dec 2016

Keywords

  • trust
  • twin design
  • heritability
  • DNA-Based Heritability

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