Feasibility of hair sampling to assess levels of organophosphate metabolites in rural areas of Sri Lanka

Duleeka Knipe, Channa Jayasumana, Sisira Siribaddana, Chamil Priyadarshana, Melissa Pearson, David Gunnell, Chris Metcalfe, Manolis Tzatzarakis, A Tsatsakis

Research output: Contribution to journalArticle (Academic Journal)peer-review

12 Citations (Scopus)
276 Downloads (Pure)

Abstract

Measuring chronic pesticide exposure is important in order to investigate the associated health effects. Traditional biological samples (blood/urine) are difficult to collect, store and transport in large epidemiological studies in settings such as rural Asia. We assessed the acceptability of collecting hair samples from a rural Sri Lankan population and found that this method of data collection was feasible. We also assessed the level of non-specific metabolites (DAPS) of organophosphate pesticides in the hair samples. The median concentration (pg/mg) of each DAP was: diethyl phosphate: 83.3 (IQI 56.0, 209.4); diethyl thiophosphate: 34.7 (IQI 13.8, 147.9); diethyl dithiophosphate: 34.5 (IQI 23.4, 55.2); and dimethyl phosphate: 3 (IQI 3, 109.7). Total diethylphosphates were recovered in >80% of samples and were positively correlated with self-reported pesticide exposure.
Original languageEnglish
Pages (from-to)207-211
Number of pages5
JournalEnvironmental Research
Volume147
Early online date16 Feb 2016
DOIs
Publication statusPublished - May 2016

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