Flexible approach to automated protein crystallization

T. J. Oldfield*, T. A. Ceska, R. L. Brady

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

16 Citations (Scopus)


An automated system for protein crystallization trials is described. Similar to commercial systems in operation, this system is readily assembled at a far lower cost. The software runs on either a microcomputer or a VAX and is both versatile and readily modified for special requirements. The system is capable of pipetting polyethylene glycol solutions accurately. Root-mean-square deviations in the accuracy of pipetted well solutions were similar to results obtained manually. Factors influencing reproducibility are discussed.

Original languageEnglish
Pages (from-to)255-260
Number of pages6
JournalJournal of Applied Crystallography
Issue numberpt 3
Publication statusPublished - 1 Jun 1991


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