Projects per year
Abstract
Investigations into protein folding have concentrated on experimentally tractable proteins with the result that membrane protein folding remains unsolved. New evidence is providing insight into the nature of the interactions stabilising the folded state of α-helical membrane proteins as well as giving hints on the character of the folding transition state. These developments show that classical methods used for water-soluble proteins can be successfully adapted for membrane proteins. The advances, coupled with increasing numbers of solved crystal structures, augur well for future research into the mechanisms of membrane protein folding.
Original language | English |
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Pages (from-to) | 8 - 13 |
Number of pages | 6 |
Journal | Current Opinion in Structural Biology |
Volume | 19 (1) |
DOIs | |
Publication status | Published - Feb 2009 |
Bibliographical note
Other: First published online 20th January 2009Fingerprint
Dive into the research topics of 'Folding scene investigation: membrane proteins'. Together they form a unique fingerprint.Projects
- 1 Finished
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MAPPING OUT TRANSITION STATES IN MEMBRANE PROTEIN FOLDING: A PHI VALUE ANALYSIS
Booth, P. J. (Principal Investigator)
1/11/05 → 1/11/09
Project: Research