Abstract
BCl3is an inexpensive electrophile which induces the borylative cyclization of a wide range of substituted alkynes to regioselectively form polycycles containing synthetically versatile C(sp2)boronate esters. It proceeds rapidly, with good yields and is compatible with a range of functional groups and substitution patterns. Intermolecular 1,2-carboboration of alkynes is also achieved using BCl3to generate trisubstituted vinyl boronate esters.
Original language | English |
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Pages (from-to) | 11245-11249 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 54 |
Issue number | 38 |
DOIs | |
Publication status | Published - 1 Jan 2015 |
Keywords
- alkynes
- boron
- cyclizations
- heterocycles
- synthetic methods