Methods: This was a retrospective cohort analysis using routinely collected data. Three different screening algorithms were assessed among patients with one or more CHC risk factors.
Results: Among the 87 348 patients attending the outpatient clinic, 5003 (6%) presented with one or more risk factors. Rapid diagnostic test (RDT) positivity was 38% overall. Approximately 60% of the CHC patients across all risk categories were in the early stage of the disease, with an aspartate aminotransferase: platelet
ratio index score <1. The sequential delays in the cascade differed between the three groups, with the interval between screening and treatment initiation being the shortest in the cohort tested with GeneXpert onsite.
Conclusions: Delays between screening and treatment can be reduced by putting in place more patientcentric testing algorithms. New strategies, to better identify and treat the hidden at-risk populations, should be developed and implemented.
- hepatitis C
- time delays
- testing and treatment algorithm
- SORT IT
- risk factors
- operational research