Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation–borylation conditions

Daniel Blair; Siying Zhong; Matthew Hesse; Nagore Zabaleta; Eddie Myers; Varinder Aggarwal

doi:10.1039/C6CC00536E

Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation–borylation conditions

Daniel Blair, Siying Zhong, Matthew Hesse, Nagore Zabaleta, Eddie Myers, Varinder Aggarwal

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

Hindered tertiary neopentyl glycol boronic esters can be prepared by using in situ lithiation–borylation of enantiopure secondary benzylic carbamates at −20 °C with full chirality transfer.

Original language	English
Pages (from-to)	5289-5292
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	30
Early online date	22 Mar 2016
DOIs	https://doi.org/10.1039/C6CC00536E
Publication status	Published - 18 Apr 2016

Research Groups and Themes

BCS and TECS CDTs
Organic & Biological

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10.1039/C6CC00536E

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This is the final published version of the article (version of record). It first appeared online via Royal Society of Chemistry at DOI: 10.1039/C6CC00536E. Please refer to any applicable terms of use of the publisher.
Final published version, 1.8 MBLicence: CC BY

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FRESCO: Efficient, Flexible Synthesis of Molecules with Tailored Shapes: from Photoswitchable Helices to anti-Cancer Compounds
Aggarwal, V. K. (Principal Investigator)
1/10/15 → 31/03/21
Project: Research
3-month Core Capability for Chemistry Research
Crosby, J. (Principal Investigator)
1/01/13 → 1/04/13
Project: Research
Changing the Synthesis Landscape with Boron at the Helm: from Chiral Organometallics to Assembly Line Synthesis
Aggarwal, V. K. (Principal Investigator)
14/05/12 → 13/01/18
Project: Research

Cite this

@article{879ca6ccb40348ea8a813ff6988db405,

title = "Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation–borylation conditions",

abstract = "Hindered tertiary neopentyl glycol boronic esters can be prepared by using in situ lithiation–borylation of enantiopure secondary benzylic carbamates at −20 °C with full chirality transfer.",

author = "Daniel Blair and Siying Zhong and Matthew Hesse and Nagore Zabaleta and Eddie Myers and Varinder Aggarwal",

year = "2016",

month = apr,

day = "18",

doi = "10.1039/C6CC00536E",

language = "English",

volume = "52",

pages = " 5289--5292",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation–borylation conditions

AU - Blair, Daniel

AU - Zhong, Siying

AU - Hesse, Matthew

AU - Zabaleta, Nagore

AU - Myers, Eddie

AU - Aggarwal, Varinder

PY - 2016/4/18

Y1 - 2016/4/18

N2 - Hindered tertiary neopentyl glycol boronic esters can be prepared by using in situ lithiation–borylation of enantiopure secondary benzylic carbamates at −20 °C with full chirality transfer.

AB - Hindered tertiary neopentyl glycol boronic esters can be prepared by using in situ lithiation–borylation of enantiopure secondary benzylic carbamates at −20 °C with full chirality transfer.

U2 - 10.1039/C6CC00536E

DO - 10.1039/C6CC00536E

M3 - Article (Academic Journal)

SN - 1359-7345

VL - 52

SP - 5289

EP - 5292

JO - Chemical Communications

JF - Chemical Communications

IS - 30

ER -

Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation–borylation conditions

Abstract

Research Groups and Themes

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Projects

FRESCO: Efficient, Flexible Synthesis of Molecules with Tailored Shapes: from Photoswitchable Helices to anti-Cancer Compounds

3-month Core Capability for Chemistry Research

Changing the Synthesis Landscape with Boron at the Helm: from Chiral Organometallics to Assembly Line Synthesis

Cite this