G-CSF treatment of cyclical neutropenia: an inclusive mathematical model

C Colijn, C Foley, M Mackey

Research output: Contribution to journalArticle (Academic Journal)peer-review

19 Citations (Scopus)

Abstract

To study the effects of different G-CSF temporal treatment schemes using a comprehensive mathematical model of the mammalian hematopoietic system that couples the pharmacokinetics of granulocyte colony-stimulating factor (G-CSF) to the hematopoietic stem cell, neutrophil, platelet, and erythrocyte dynamics.
Translated title of the contributionG-CSF treatment of cyclical neutropenia: an inclusive mathematical model
Original languageEnglish
Pages (from-to)898 - 907
Number of pages10
JournalExperimental Hematology
Volume35(6)
DOIs
Publication statusPublished - Jun 2007

Bibliographical note

Publisher: Elsevier BV

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