G-CSF treatment of cyclical neutropenia: an inclusive mathematical model

C Colijn; C Foley; M Mackey

doi:10.1016/j.exphem.2007.02.015

G-CSF treatment of cyclical neutropenia: an inclusive mathematical model

C Colijn, C Foley, M Mackey

University of Bristol

Research output: Contribution to journal › Article (Academic Journal) › peer-review

20 Citations (Scopus)

Abstract

To study the effects of different G-CSF temporal treatment schemes using a comprehensive mathematical model of the mammalian hematopoietic system that couples the pharmacokinetics of granulocyte colony-stimulating factor (G-CSF) to the hematopoietic stem cell, neutrophil, platelet, and erythrocyte dynamics.

Translated title of the contribution	G-CSF treatment of cyclical neutropenia: an inclusive mathematical model
Original language	English
Pages (from-to)	898 - 907
Number of pages	10
Journal	Experimental Hematology
Volume	35(6)
DOIs	https://doi.org/10.1016/j.exphem.2007.02.015
Publication status	Published - Jun 2007

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Publisher: Elsevier BV

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10.1016/j.exphem.2007.02.015

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VP8-4NTXG96-B&_user=121739&_coverDate=06%2F30%2F2007&_rdoc=10&_fmt=full&_orig=browse&_srch=doc-info(%23toc%236200%232007%23999649993%23657916%23FLA%23display%23Volume)&_cdi=6200&_sort=d&_docanchor=&view=c&_ct=20&_acct=C000010018&_version=1&_urlVersion=0&_userid=121739&md5=a1cd71634880640e06e29c7100d3bb9d

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title = "G-CSF treatment of cyclical neutropenia: an inclusive mathematical model",

abstract = "To study the effects of different G-CSF temporal treatment schemes using a comprehensive mathematical model of the mammalian hematopoietic system that couples the pharmacokinetics of granulocyte colony-stimulating factor (G-CSF) to the hematopoietic stem cell, neutrophil, platelet, and erythrocyte dynamics.",

author = "C Colijn and C Foley and M Mackey",

note = "Publisher: Elsevier BV",

year = "2007",

month = jun,

doi = "10.1016/j.exphem.2007.02.015",

language = "English",

volume = "35(6)",

pages = "898 -- 907",

journal = "Experimental Hematology",

issn = "1873-2399",

publisher = "Elsevier Inc.",

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T1 - G-CSF treatment of cyclical neutropenia: an inclusive mathematical model

AU - Colijn, C

AU - Foley, C

AU - Mackey, M

N1 - Publisher: Elsevier BV

PY - 2007/6

Y1 - 2007/6

N2 - To study the effects of different G-CSF temporal treatment schemes using a comprehensive mathematical model of the mammalian hematopoietic system that couples the pharmacokinetics of granulocyte colony-stimulating factor (G-CSF) to the hematopoietic stem cell, neutrophil, platelet, and erythrocyte dynamics.

AB - To study the effects of different G-CSF temporal treatment schemes using a comprehensive mathematical model of the mammalian hematopoietic system that couples the pharmacokinetics of granulocyte colony-stimulating factor (G-CSF) to the hematopoietic stem cell, neutrophil, platelet, and erythrocyte dynamics.

U2 - 10.1016/j.exphem.2007.02.015

DO - 10.1016/j.exphem.2007.02.015

M3 - Article (Academic Journal)

C2 - 17533044

SN - 1873-2399

VL - 35(6)

SP - 898

EP - 907

JO - Experimental Hematology

JF - Experimental Hematology

ER -

G-CSF treatment of cyclical neutropenia: an inclusive mathematical model

Abstract

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