G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration

Vincent Degos; Stéphane Peineau; Cora Nijboer; Angela M Kaindl; Stéphanie Sigaut; Géraldine Favrais; Frank Plaisant; Natacha Teissier; Elodie Gouadon; Alain Lombet; Elie Saliba; Graham L Collingridge; Mervyn Maze; Ferdinando Nicoletti; Cobi Heijnen; Jean Mantz; Annemieke Kavelaars; Pierre Gressens

doi:10.1002/ana.23868

G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration

Vincent Degos
, Stéphane Peineau
, Cora Nijboer
, Angela M Kaindl
, Stéphanie Sigaut
, Géraldine Favrais
, Frank Plaisant
, Natacha Teissier
, Elodie Gouadon
, Alain Lombet
, Elie Saliba
, Graham L Collingridge
, Mervyn Maze
, Ferdinando Nicoletti
, Cobi Heijnen
, Jean Mantz
, Annemieke Kavelaars
, Pierre Gressens

Research output: Contribution to journal › Article (Academic Journal) › peer-review

45 Citations (Scopus)

Abstract

The concept of inflammation-induced sensitization is emerging in the field of perinatal brain injury, stroke, Alzheimer disease, and multiple sclerosis. However, mechanisms underpinning this process remain unidentified.

Original language	English
Pages (from-to)	667-78
Number of pages	12
Journal	Annals of Neurology
Volume	73
Issue number	5
DOIs	https://doi.org/10.1002/ana.23868
Publication status	Published - May 2013

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Degos, V., Peineau, S., Nijboer, C., Kaindl, A. M., Sigaut, S., Favrais, G., Plaisant, F., Teissier, N., Gouadon, E., Lombet, A., Saliba, E., Collingridge, G. L., Maze, M., Nicoletti, F., Heijnen, C., Mantz, J., Kavelaars, A., & Gressens, P. (2013). G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration. Annals of Neurology, 73(5), 667-78. https://doi.org/10.1002/ana.23868

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title = "G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration",

abstract = "The concept of inflammation-induced sensitization is emerging in the field of perinatal brain injury, stroke, Alzheimer disease, and multiple sclerosis. However, mechanisms underpinning this process remain unidentified.",

author = "Vincent Degos and St{\'e}phane Peineau and Cora Nijboer and Kaindl, \{Angela M\} and St{\'e}phanie Sigaut and G{\'e}raldine Favrais and Frank Plaisant and Natacha Teissier and Elodie Gouadon and Alain Lombet and Elie Saliba and Collingridge, \{Graham L\} and Mervyn Maze and Ferdinando Nicoletti and Cobi Heijnen and Jean Mantz and Annemieke Kavelaars and Pierre Gressens",

note = "Copyright {\textcopyright} 2013 American Neurological Association.",

year = "2013",

month = may,

doi = "10.1002/ana.23868",

language = "English",

volume = "73",

pages = "667--78",

journal = "Annals of Neurology",

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Degos, V, Peineau, S, Nijboer, C, Kaindl, AM, Sigaut, S, Favrais, G, Plaisant, F, Teissier, N, Gouadon, E, Lombet, A, Saliba, E, Collingridge, GL, Maze, M, Nicoletti, F, Heijnen, C, Mantz, J, Kavelaars, A & Gressens, P 2013, 'G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration', Annals of Neurology, vol. 73, no. 5, pp. 667-78. https://doi.org/10.1002/ana.23868

TY - JOUR

T1 - G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration

AU - Degos, Vincent

AU - Peineau, Stéphane

AU - Nijboer, Cora

AU - Kaindl, Angela M

AU - Sigaut, Stéphanie

AU - Favrais, Géraldine

AU - Plaisant, Frank

AU - Teissier, Natacha

AU - Gouadon, Elodie

AU - Lombet, Alain

AU - Saliba, Elie

AU - Collingridge, Graham L

AU - Maze, Mervyn

AU - Nicoletti, Ferdinando

AU - Heijnen, Cobi

AU - Mantz, Jean

AU - Kavelaars, Annemieke

AU - Gressens, Pierre

PY - 2013/5

Y1 - 2013/5

N2 - The concept of inflammation-induced sensitization is emerging in the field of perinatal brain injury, stroke, Alzheimer disease, and multiple sclerosis. However, mechanisms underpinning this process remain unidentified.

AB - The concept of inflammation-induced sensitization is emerging in the field of perinatal brain injury, stroke, Alzheimer disease, and multiple sclerosis. However, mechanisms underpinning this process remain unidentified.

U2 - 10.1002/ana.23868

DO - 10.1002/ana.23868

M3 - Article (Academic Journal)

C2 - 23494575

SN - 1531-8249

VL - 73

SP - 667

EP - 678

JO - Annals of Neurology

JF - Annals of Neurology

IS - 5

ER -

G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration

Abstract

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